OBJECTIVES We established population-based reference limits for plasma total homocysteine (tHcy) according to creatinine. DESIGN AND METHODS In 7042 middle-aged and elderly subjects from the Hordaland Homocysteine Study, we used statistical modeling to establish nomograms for tHcy according to creatinine in the whole population and in folate-replete and healthy subgroups. RESULTS When plott...

Amin A. Nanji, Division of Clinical Chemistry, Vancouver General Hospital, Vancouver V5Z1M9 (Canada) Dear Sir, Analytical and biologic variations in serum and urinary creatinine may account for up to 33% variability in creatinine clearance calculations [1]. We wish to report on the marked variability of creatinine clearance in patients receiving total parenteral nutrition (TPN). 18 of 93 patien...

objective(s): global cerebral ischemia-reperfusion (gcir) causes disturbances in brain functions as well as other organs such as kidney. our aim was to evaluate the protective effects of ellagic acid (ea) on certain renal disfunction after gcir. materials and methods: adult male wistar rats (n=32, 250-300 g) were used. gcir was induced by bilateral vertebral and common carotid arteries occlusio...

the purpose of this study was to determine the number of prescribed antibiotics being appropriately adjusted and to assess antibiotics with the highest incorrect dosing based on the patient’s renal function according to distinguished guidelines. the study was conducted at a 446-bed university hospital. one hundred and fifty patients admitted through different wards of the hospital were included...

background:the first step in diagnosis of diabetic nephropathy is measurement ofalbumin in a spot urine sample. the aim of this study was assessment of the accuracy of urinary albumin to creatinine ratio (uacr) in random urine specimens (rus) for microalbuminuria and macroalbuminuria screening in iranian diabetic patients. methods:a total of 200 diabetic patients participated to our study. 24 h...

background because of difficulty in obtaining a 24-hour urine collection in children, a random sample of urine is often used to calculate the urinary calcium to creatinine ratio. urinary calcium excretion might be influenced by genetic, geographic area, etc. in this study, the value of urinary calcium, creatinine, sodium and potassium excretion and age–related reference values for urine calcium...