Serum enzyme studies were made on 43 (37 male, 6 female) consecutive patients with ankylosing spondylitis. Serum creatine phosphokinase (CPK) activity was raised above 55 IU/l in 24 (65%) of 37 male patients (range 29-165 IU/l, mean 68) as compared with 2 (4%) out of 47 male controls (range 14-85 IU/l, mean 33: P less than 0-001); levels were greater than 35 IU/l in six (100%) out of six female...

OBJECTIVE Accurate and rapid diagnosis of acute myocardial infarction (MI) is of major medical and economic importance. The objective of this study was to identify unstimulated whole saliva creatine phosphokinase (CPK) in patients with acute MI. SUBJECTS AND METHODS A case-control study was carried out in 30 normal healthy individuals and 30 patients with acute MI were hospitalized in CCU of ...

Since creatine phosphokinase (CPK) is found predominantly in myocardial and skeletal muscle cells, in contrast to cells participating in the inflammatory response, it was considered likely that measurement of activity of this enzyme in the heart would provide a sensitive and relatively specific index of the extent of ischemic injury following acute coronary artery occlusion. Accordingly, CPK ac...

Creatine Phosphokinase-Linked Immunoglobulin in a Patient with Hypokalemic Myopathy Dr. H. Arai, Department of Neurology, Motojima General Hospital, Ota, Gunma 373 (Japan) A macromolecular complex between creatine phosphokinase (CPK) and an immunoglobulin [1], termed macro-CPK type 1 [2, 3], is most likely an immune complex [4, 5] and has been identified in a variety of diseases including ische...

Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone or, more rarely, from their impaired activity at tissue level. This study was designed to estimate the Creatine phosphokinase, serum creatinine level and estimated glomerular filtration rate in hypothyroidism cases and to assess the correlation with T4 and TSH. This Study included 62 patients of hypothyro...

CLINICAL CHEMISTRY, Vol. 24, No. 6, 1978 1085 patterns, assayed by fluorescence, occurring in the serum of patients with end-stage renal disease requiring maintenance hemodialysis. Clin. Chim. Acta 70, 333 (1976). 3. Coolen, R. B., and Herbstman, R., Artifactual brain (BB) creatine kinase (CK) isoenzyme in kidney transplant and renal dialysis patients. Clin. Chem. 23, 1142 (1977). Abstract. 4. ...

A 19-year-old white man with familial hypokalemic periodic paralysis developed evidence of cardiac dysfunction during a episode of flaccid paralysis. This consisted of elevated total creatine phosphokinase (CPK), an increased myocardial fraction of CPK (myocardial band), alteration in the lactic dehydrogenase isoenzyme pattern, severe bradycardia, and evidence of left ventricular dysfunction. T...