OBJECTIVE Among rheumatoid arthritis (RA) patients, the intensity of pain may be out of proportion to the severity of peripheral inflammation. This observation suggests that mechanisms of central nervous system pain amplification, such as diminished conditioned pain modulation (CPM), may play a role in enhancing pain perception among some RA patients. This study was undertaken to examine the le...

192 Background: Rates of unilateral (UM) and contralateral prophylactic mastectomy (CPM) for early-stage breast cancer (ESBC) have been increasing. To understand this increase we sought the perspectives of patients who chose UM+/-CPM and treating surgeons. METHODS Applying the Health-Belief Model, we completed a qualitative study examining the surgeon's practice and patient's decision-making ...

Central pontine myelinolysis (CPM) is a rare neurologic entity of varied etiology characterized by the destruction of the myelin sheath in pontine structures. Initially described in chronic alcohol abuse and malnourished patients, CPM has also been associated with the rapid correction of hyponatremia and alterations in blood glucose homeostasis. Here we present a case of a man experiencing CPM ...

Magnetic resonance imaging (MRI) was performed in two patients in whom a clinical diagnosis of central pontine myelinolysis (CPM) had been made. MRI showed lesions in the pons in both cases about 2 years after the illness, at a time when the spastic quadriparesis and pseudobulbar palsy had recovered. The persisting abnormal signals in CPM are likely to be due to fibrillary gliosis. Persistence ...

Although many quantitative risk assessment models have been proposed in literature, their use construction practice remain limited due to a lack of domain-specific models, tools, and application examples. This is especially true wind farm construction, where the state-of-the-art integrated Monte Carlo simulation critical path method (MCS–CPM) approach has yet be demonstrated. The present case s...

Purpose: Breast conservation has been shown to have similar mortality rates as compared to mastectomy. We hypothesized that variables involving the patient, tumor and surgeon influence the treatment a patient may choose. Methods: Retrospective review of a prospectively maintained database of all patients who underwent surgical treatment for breast cancer between 2000 and 2009 was performed. Mul...

BACKGROUND Central pontine myelinolysis (CPM) is a demyelinating disorder of the central basis pontis that is often associated with osmotic stress. The aquaporin water channels (AQPs) have been pathogenically implicated because serum osmolarity changes redistribute water and osmolytes among various central nervous system compartments. RESULTS We characterized the immunoreactivity of aquaporin...

Space-time coding has shown great promise for digital transmission in wireless communication links, especially when the channel response is known at the receiver. Space time coding combined with continuous phase modulation (CPM) can offer better tradeoffs in bandwidth and power efficiency. Because of the memory inherent in CPM, channel estimation is often harder than for linear modulations. In ...

This letter investigates a serially concatenated convolutional coded M-ary continuous phase modulation (CPM). Using the decomposition model of a CPM system, the soft-input-soft-output detectors for M-ary CPM is investigated in detail. Based on these, the performance of bit-interleaved coded-modulation (BICM) schemes is studied. Simulation results show that due to the presence of the conversion ...

Conditioned pain modulation (CPM) paradigms have been used in various studies with healthy and non-healthy adult populations in an attempt to elucidate the mechanisms of pain processing. However, only a few studies so far have applied CPM in pediatric populations. Studies finding associations with chronic pain conditions suggest that deficiencies in underlying descending pain pathways may play ...