We present a safe and convenient cross-coupling strategy for the large-scale synthesis of biaryls, commercially important structures often found in biologically active molecules. In contrast to traditional cross-couplings, which require the prior preparation of organometallic reagents, we use a copper catalyst to generate the carbon nucleophiles in situ, via decarboxylation of easily accessible...

We study the polarization of τ leptons produced at a γγ collider in the reaction γγ → ττ as a possible probe of the Higgs (φ) contribution to this process and consequently of the Higgs CP property. We construct polarization asymmetries which can probe the γγφ and φττ couplings for both the CP-conserving and the CP-violating cases. We demonstrate the use of these asymmetries by analysing the CP-...

We calculate the cross section of Higgs boson production in the reaction e + e − → ν ¯ νb ¯ b for the case of left and right longitudinally polarized electron beam. Complete set of signal and irreducible background diagrams is considered. We propose a new critical test to identify the Higgs boson provided by the ratio of cross sections with left and right beam polarization. This quantity is sen...

In this paper, we developed a new method using 4-bromoacetophenone as the starting material, with tosylhydrazide and two arylboronic acids using Barluenga and Suzuki couplings in a four-component one-pot reaction to afford the target product 4-benzyl-1,1'-biphenyls. This system that we have developed enables the use of easily accessible starting materials and can be employed on a wide variety o...

The title azaazulene 3 was synthesized either by reaction of tropone with N-{(2-pyridyl)acetyl}pyridinium iodide in the presence of ammonium acetate or by palladium-catalyzed cross-couplings between 2-halo-1-azaazulene and 2-substituted pyridine. The compound shows relatively stronger basicity compared with 2,2’-bipyridyl. While 3 showed no emission from the S1 state but from the S2 state like ...

The critical properties of the Frank model of spontaneous chiral synthesis are discussed by applying results from the field theoretic renormalization group (RG). The long time and long wavelength features of this microscopic reaction scheme belong to the same universality class as multicolored directed percolation processes. Thus the following RG fixed points (FPs) govern the critical dynamics ...

A product analysis was m ade for the reaction between som e aromatic am ines and 3-bromocamphor (2), which was invariably transformed into camphor (3) and eventually aryliminocamphor. The tertiary N ,N -dim ethylanilines were oxidized through a com plex sequence o f couplings and rearrangements to a number o f diam ines of the diphenylm ethane type. Aniline (4) was also successful in the reduct...

One of the major goals of the CERN Large Hadron Collider (LHC) is the understanding of the mechanism of electroweak (EW) symmetry breaking [1]. In this context, vector-boson fusion (VBF) processes form a promising class of reactions: Higgs production in VBF, i.e. the reaction qq → qqH, has been proposed as a particularly clean channel for the discovery of the Higgs boson and a later determinati...

Readily available natural α-amino acids are one of nature's most attractive and versatile building blocks in synthesis of natural products and biomolecules. Peptides and N-heterocycles exhibit various biological and pharmaceutical functions. Conjugation of amino acids or peptides with N-heterocycles provides boundless potentiality for screening and discovery of diverse biologically active molec...