A Data Warehouse (DW) is a database that stores a copy of operational data with an optimized structure for query and analysis. There are many facets due to the number of variables that are needed to consider in the integration phase design. It is not easy to generate and maintain the integrated scheme. In this paper we describe a spatio-temporal extension of an ontology language which facilitat...

The motor protein non-muscle myosin II is a major driver of the movements that sculpt three-dimensional organs from two-dimensional epithelia. The machinery of morphogenesis is well established but the logic of its control remains unclear in complex organs. Here we use live imaging and ex vivo culture to report a dual role of myosin II in regulating the development of the Drosophila wing. First...

Current Internet users see the combination of World-wide Web (WWW) and electronic mail as a synonym for the Internet. While WWW is excellent for easy and fast dissemination of information and email facilitates efficient communication, a means for wide-spread, threaded discussion and interchange of information among large groups of users is still necessary. WWW has experienced a tremendous innov...

In the Drosophila leg disc, wingless (wg) and decapentaplegic (dpp) are expressed in a ventral-anterior and dorsal-anterior stripe of cells, respectively. This pattern of expression is essential for proper limb development. While the Hedgehog (Hh) pathway regulates dpp and wg expression in the anterior-posterior (A/P) axis, mechanisms specifying their expression in the dorsal-ventral (D/V) axis...