As per definition, the bioreactor is the designed space where biological reactions take place. Hence, the bioreactor is essentially an engineering achievement and its design a challenge for bioengineers. The bioreactor should create a biosphere that as profoundly and adequately as possible provides the ideal environment for the biological reaction. The path for reaching, attaining, andmaintaini...

Experimental studies of two-phase anaerobic digestion corn steep liquor in semi-continuous automatic and semi-automatic modes operation a cascade two bioreactors with monitoring control systems were performed. Corn liquor—a waste product from the process treating grain for starch extraction—was used as substrate simultaneous hydrogen methane production. The daily yields biohydrogen bioreactor 1...

This study is pertaining to the production of penicillin G acylase (PGA) by Bacillus subtilis 8105MU331 in which PGA gene, under the control of thermal-induced promoter, was integrated. The key process parameters including induced-temperature, induced-time, and culture temperature were optimized in flask culture. A three-stage cultivation process was developed for PGA production with the expres...

The main target in the production of monoclonal antibodies (MAbs) is reduction of operating costs. One of the pertinent challenges is improving the yield of MAbs through the reduction of secondary metabolic products. Therefore searching for an optimal nutrients supplying strategy becomes mandatory. This study is about the influence of by-products together with the dead cell concentration upon t...

This paper deals with set membership state estimation for continuous-time systems from discrete-time measurements, in the unknown but bounded error framework. The classical predictor-corrector approach to state estimation uses interval Taylor methods for solving the prediction phase, which are known to have poor performance in presence of large model or input uncertainty. In this paper, we show...

selected genotypes of sugar beet are often maintained by conventional propagation, but much faster rates of multiplication can be now obtained through micropropagation. on the other hand, plant micropropagation using bioreactors can decrease the cost of production and makes it an economical method. in this research, the possibility of using bioreactor and optimization of the tissue culture proc...

This study discusses the retention of Ni(II) by Arthrobacter viscosus supported on zeolite 13 X in batch mode and in continuous mode, at laboratory scale and at pilot scale. The maximum adsorption capacities of 28.37, 20.21 and 11.13 mg/g were recorded for lab scale batch, for continuous lab scale minicolumns and for pilot scale bioreactors, respectively. The Sips isotherm and pseudo second ord...