نتایج جستجو برای: conjugate sequence
تعداد نتایج: 445679 فیلتر نتایج به سال:
Small interfering RNA (siRNA)-based drugs require chemical modifications or formulation to promote stability, minimize innate immunity, and enable delivery to target tissues. Partially modified siRNAs (up to 70% of the nucleotides) provide significant stabilization in vitro and are commercially available; thus are commonly used to evaluate efficacy of bio-conjugates for in vivo delivery. In con...
A fluorescent probe for glutathione (GSH) detection was developed. Our study indicates a possible mechanism which couples a conjugate addition and micelle-catalyzed large membered ring formation/elimination sequence. This method enables excellent selectivity towards GSH over other biological thiols such as cysteine (Cys) and homocysteine (Hcy). The proposed method is precise with a relative sta...
A type II beta-turn-like structured ferrocene-dipeptide conjugate through intramolecular hydrogen bonding was formed by the introduction of only one minimum-sized peptide chain of the heterochiral sequence (-L-Ala-D-Pro-NH-4-Py or -D-Ala-L-Pro-NH-4-Py) into the ferrocene scaffold, which was subjected to a metal-directed assembly with [Pd(MeCN)(4)](BF(4))(2) to afford the beta-turn-structure-ass...
Temporal superresolution produces a video sequence of high temporal resolution (HTR), i.e. frame rate, from a set of video sequences of low temporal resolution (LTR). A method for preconditioning large systems of linear equations arising in temporal video superresolution problems is presented. We show that circulant block preconditioners can accelerate the convergence of iterative techniques su...
where [(z) is continuous, it is clear that given an e>0 and a complete orthonormal sequence {<£„}, there exists an N = N(D, K, £, {„}) such that m^N an...
A study is presented of the nanomechanical phenomena experienced by nanoparticle-conjugated biomolecules. A thermodynamic framework is developed to describe the binding of thrombin-binding aptamer (TBA) to thrombin when the TBA is conjugated to nanorods. Binding results in nanorod aggregation (viz. directed self-assembly), which is detectable by absorption spectroscopy. The analysis introduces ...
The transformed values ẑpk are complex, but for each value of p the ẑ p k form a Hermitian sequence (i.e., ẑpn k is the complex conjugate of ẑ p k), so they are completely determined by mn real numbers (since ẑ p 0 is real, as is ẑpn=2 for n even). Alternatively, given m Hermitian sequences of n complex data values zpj , this routine simultaneously calculates their inverse (backward) discrete F...
By considering electromagnetic scattering problems as examples, a study of the performance and scalability of the conjugate gradient squared (CGS) algorithm on two MIMD machines is presented. A modified CGS (MCGS) algorithm, where the synchronization overhead is effectively reduced by a factor of two, is proposed in this paper. This is achieved by changing the computation sequence in the CGS al...
A conjecture of Grone and Merris states that for any graph G, its Laplacian spectrum, Λ(G), is majorized by its conjugate degree sequence, D∗(G). That conjecture prompts an investigation of the relationship between Λ(G) and D∗(G), and Merris has characterized the graphs G for which the multisets Λ(G) and D∗(G) are equal. In this paper, we provide a constructive characterization of the graphs G ...
Recently, Lal [9] has determined the degree of approximation of function belonging to Lip α and weighted classes using Product C . Np summability with non-increasing weights{pn}. In this paper, we determine the degree of approximation of function f̃ , conjugate to a 2π-periodic function f belonging to Lip (ξ (t), r)−class using semi-monotonicity on the generating sequence {pn} with proper set of...
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