Ocular toxoplasmosis is commonly attributed to prenatally acquired (congenital) infection unless there is clear evidence that infection was acquired postnatally. We challenge this view by comparing the risks of ocular disease caused by prenatal and postnatal toxoplasmosis. As the history, clinical appearances, and serological findings associated with the two aetiologies are frequently indisting...

The main purpose of the present study was to examine if there is difference in terms of incidence rates of congenital toxoplasmosis among populations assisted in public and private hospitals from Uberlândia, state of Minas Gerais, Brazil. A total of 805 serum samples from cord blood were collected, being 500 from public hospital and 305 from private hospital, and all patients answered a questio...

Over the past two decades, molecular diagnosis of toxoplasmosis, which is based on the detection of T. gondii DNA in clinical samples, became an indispensable laboratory test. This method is independent of the immune response, and depending on methodological approach, may facilitate more accurate diagnosis, especially in cases in which inadequacy of conventional methods is faced with deteriorat...

Introduction Mrs M., a 30 year-old lecturer in psychology is expecting her second baby. Her first baby was born while she was on sabbatical in France. During that pregnancy she was screened for Toxoplasmosis, found to be non-immune and had repeated monthly screening throughout her pregnancy. The consensus in France is to screen all pregnant women for toxoplasmosis at the first visit, and to off...

Toxoplasmosis is a major and preventable cause of severe visual handicap and blindness in young people. Congenital toxoplasmosis, as well as toxoplasmosis in immuno-compromised patients, is a serious, sometimes fatal disease. I 2 Toxoplasmic encephalitis has gained importance as a leading cause of AIDS related mortality. Toxoplasma gondii, the aetiological agent of human and animal toxoplasmosi...

To estimate the prevalence of congenital toxoplasmosis, Chagas disease, cytomegalovirus, and rubella, blood samples on dried blood spot (DBS) from neonates (day 3-20 of life) were screened for immunoglobulin (Ig) M against Toxoplasma gondii, cytomegalovirus, rubella virus, and IgG against Trypanosoma cruzi by methods used for serum and adapted for use with DBS. Positive samples were further ana...