conclusions the frequency of nis in this hospital was lower in comparison with other worldwide studies. however, low incidence of health care-associated infections in our study may be due to under diagnosis and underreporting of such infections by health care staff. results the incidence of nis was low (i.e. < 2%). among 16936 admitted patients in this hospital, 174 patients (79 males and 95 fe...

introduction: infective endocarditis is a rare, fatal ,with high morbidity in children, since infective endocarditis in children was not assessed in our conditions so our study was attempted.   material and methods: this cross-sectional  study  include 19 patients less than 18 years old  with endocarditis   were hospitalized in the department of pediatric cardiology( university of mashhad medic...

Severe congenital neutropenia (SCN) is a primary immunodeficiency disease characterized by early onset of severe bacterial infection and persistent severe neutropenia. We describe an SCN patient with a history of recurrent infections. The clinical course was complicated by necrosis of the nasal cartilage due to mucormycosis. Molecular studies revealed a homozygous germline HAX1 mutation. Fungal...

Rheuniatic fever is a recurrent disease which frequently can be prevented. Infection with group A streptococci precipitates both initial and recurrent attacks; therefore, prevention of rheumatic fever and rheumatic heart disease depends upon the control of streptococcal infections. This may be accomplished, one by prevention of streptococcal infections in rheumatic subjects, and, two by early a...

ogy of cytomegalovirus infections during pregnancy and infancy. Scand J Infect Dis 10:165, 1987 11. Ahlfors K, Ivarsson S-A, Johnsson T, Svensson I: Congenital and acquired cytomegalovirus infections. Acta Paediatr Scand 67:321, 1978 12. Stuart-Harris C: The epidemiology and clinical presentation of herpes virus infections. J Antimicrob Chemother 12:1, 1983 13. Lamy ME, Favart AM, Cornue C, Men...

Introduction: Infective endocarditis is a rare, fatal ,with high morbidity in children, Since infective endocarditis in children was not assessed in our conditions so our study was attempted.   Material and Methods: This cross-sectional  study  include 19 patients less than 18 years old  with endocarditis   were hospitalized in the Department of Pediatric Cardiology( University of Mashhad...

Rheuniatic fever is a recurrent disease which frequently can be prevented. Infection with group A streptococci precipitates both initial and recurrent attacks; therefore, prevention of rheumatic fever and rheumatic heart disease depends upon the control of streptococcal infections. This may be accomplished, one by prevention of streptococcal infections in rheumatic subjects, and, two by early a...

Chryseobacterium indologenes is a rare cause of infection in children. The organism causes infections mostly in hospitalised patients with severe underlying diseases. The choice of an effective drug for the treatment of infections due to C. indologenes is difficult as the organism has a limited spectrum of antimicrobial sensitivity. We present a case of nosocomial septicemia caused by C. indolo...

neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. it manifests as dic and extensive subcutaneous thrombosis. the condition is often fatal unless there is prompt diagnosis, and judicious therapy. the most important causes of this condition are infections and congenital deficiency of anticoagulant proteins c and s.in the case of pc (p...

introduction: congenital anomalies of the cochlea and labyrinth can be associated with meningitis and varying degrees of hearing loss or deafness. despite antibiotics, meningitis remains a life threatening complication.   case report: we report a case of recurrent meningitis following episodes of otitis media in a cochlear implantee child with bilateral vestibulocochlear malformation, due to fi...