Abstract Background Congenital pulmonary airway malformation (CPAM) with partial anomalous venous connection presenting as episodic retrosternal chest pain on exertion in an adult has not been described. Case presentation A 21-year-old female, non-smoker, presented a 4-year history of sharp, episodic, pains brought exercise. contrast-enhanced computed tomography (CT) scan showed grossly overinf...

Congenital heart disease (CHD) is the most common human birth defect worldwide,1 taking a tremendous toll on affected families, caregivers, and healthcare systems. Approximately 40 000 children are born each year in the United States with a heart malformation, and at least another 40 000 are born annually with subclinical malformations that result in heart disease later in adulthood. Significan...

Dandy-Walker syndrome (DWS) is a rare brain malformation involving the cerebellum, and the fluid filled spaces around it, usually detected during the antenatal period or the early infancy. Clinically, it is characterized by mental retardation, developmental delay as well as cerebellar ataxia. It has been frequently associated with other conditions such as congenital heart diseases, primary hypo...

Coarctation of the aorta (CoA) is a congenital cardiac malformation that is well understood. Despite being well characterized, CoA is a commonly missed congenital heart disease (CHD) during the newborn period. We report a full-term nine-day-old male who presented to the pediatric emergency department (ED) with isolated tachypnea. After an initial sepsis workup, subsequent investigations reveale...

IFE expectancy and the degree of invalidism have been considered a function of the type of cardiac malformation in patients with congenital heart disease. When the abnormality involves a large communication between the ventricles or great vessels, however, the pulmonary vascular bed plays an important role in governing prognosis. The following group of congenital malformations are involved in t...

Amniotic band syndrome is a collection of fetal malformations associated with fibrous bands that appear to entangle or entrap various fetal parts in utero leading to deformation, malformation, or disruption. Ectopia cordis is a rare congenital defect in fusion of the anterior chest wall resulting in extrathoracic location of the heart. In this article, we report a rare case of ectopia cordis an...

Interrupted aortic arch is an extremely rare congenital malformation representing about 1% of congenital heart disease. Early symptoms usually occur early in the neonatal period and clinical deterioration is often rapid and long-term prognosis is limited. Nonetheless, this condition has been identified later in adult life in rare cases. We report a case in an adult male with absence of hyperten...