the rare form of skeletal dysplasia is thanatophoric dysplasia. the meaning for thanatophoric dysplasia is death bearing which is derived from greek word. it occurs 1in 20,000 to 50,000. it is mainly due to mutations in the fibroblast growth factor receptor 3gene. features of thanatophoric dysplasia are frontal bossing, prominent eyes, narrow thorax, protruded abdomen and bowed legs. the knowle...

OBJECTIVE To evaluate the National Congenital Anomaly System (NCAS). METHODS The NCAS in England and Wales based at the Office for National Statistics and the various regional registers that exchange data with it were examined, based on guidelines for evaluating public health surveillance systems, published by the Centres for Disease Control (CDC). Data relating to congenital anomaly notifica...

Congenital anomaly of the inferior vena cava (IVC) is a well described phenomenon [1,2]. These anomalies include complete absence, partial absence or duplication of the IVC [3]. Such anomalies of the IVC are seen more frequently in those with other congenital cardiac anomalies (0.6%–2%) [4]. This congenital condition can be discovered incidentally, or due to symptoms of associated congenital he...