A new circuit technique for voltage gain enhancement in CMOS op amp design suitable for low voltage and high speed operation is presented in this paper. A negative conductance is used to cancel the positive output conductance of an amplifier thereby reducing the total equivalent output conductance and increasing the voltage gain of the amplifier. The negative conductance is derived from the out...

The onset response pattern displayed by octopus cells has been attributed to intrinsic membrane properties, low membrane impedance, and/or synaptic inputs. Although the importance of a low membrane impedance generally is acknowledged as an essential component, views differ on the role that ion channels play in producing the onset response. In this study, we use a computer model to investigate t...

We present numerical renormalization group calculations for the zero-bias conductance of quantum dots made from semiconducting carbon nanotubes. These explain and reproduce the thermal evolution of the conductance for different groups of orbitals, as the dot-lead tunnel coupling is varied and the system evolves from correlated Kondo behavior to more weakly correlated regimes. For integer fillin...

The charge on the side chain of the internal pore residue lysine 519 (K519) of the Torpedo ClC-0 chloride (Cl-) channel affects channel conductance. Experiments that replace wild-type (WT) lysine with neutral or negatively charged residues or that modify the K519C mutant with various methane thiosulfonate (MTS) reagents show that the conductance of the channel decreases when the charge at posit...

Although activation of a sea urchin egg by sperm leads to three phases of membrane conductance increase in the egg, the mechanism by which the sperm causes these conductance changes is not known. We used the loose patch clamp technique to localize the conductance changes in voltage clamped eggs. A patch of the egg's membrane was isolated from the bath by pressing the loose patch clamp pipette a...

Neuromorphic computing embraces the “device history” offered by many analog non-volatile memory (NVM) devices to implement the small weight changes computed by a gradient-descent learning algorithm such as backpropagation. Deterministic and stochastic imperfections in the conductance response of real NVM devices can be encapsulated for modeling within a pair of “jump-tables.” Such jump-tables d...

1. Pressure-sensitive mechanosensory (P) neurones of the leech Hirudo medicinalis produce two responses to serotonin (5-HT): activation of a Cl- conductance and of a non-selective monovalent cation conductance. The effects of channel blockers, the receptor pharmacology and the second-messenger dependence of these responses were studied in voltage-clamped P cells in culture. Antagonists were app...

When present in micromolar amounts on one side of phospholipid bilayer membranes, monazomycin (a positively charged, polyene-like antibiotic) induces dramatic voltage-dependent conductance effects. Voltage clamp records are very similar in shape to those obtained from the potassium conductance system of the squid axon. The steady-state conductance is proportional to the 5th power of the monazom...

in order to evaluate the effects of drought stress and planting method on some physiological and biochemical characteristics of two chickpea cultivars (cicer arietinum l.) an experiment was conducted at the research station of college of agriculture, shiraz university using a split factorial based on randomized complete block design in four replications. the main factor was stopping irrigation ...