conclusions our results suggested that cb-nk cells progenitors could proliferate and differentiate on feeder layer of amnion membrane mscs in combination with specific cytokines to produce nk cells for immunotherapy. results combination of cytokines and msc layer yielded significant fold expansion in comparison with cytokines without feeder conditions (day 7: 5.2 ± 1.12 and 2 ± 0.78, respective...

background: β-thalassemia considers worldwide public health disorders. novel fetal hemoglobin inducer agents such as thalidomide and sodium butyrate have been attended for ameliorating clinical complications of such disorders. material and methods: we used thalidomide and sodium butyrate for increasing the level of fetal hemoglobin in erythroid progenitors. briefly, after isolation of cd133+ st...

Pre-term (35 weeks) 1-day old (2.1kg) male child delivered by Caesarean section (in view of meconium stained liquor) presented with a fleshy red mass protruding from right side of umbilical cord since birth. Examination revealed soft mass (mummified mass of bowel) attached with abdominal wall just right to umbilical cord (Fig.1). Laboratory investigations were normal. Abdominal X-ray gave impre...

Umbilical cord blood is an alternative hematopoietic stem cell source for patients with hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation. Initially, umbilical cord blood transplantation was limited to children, given the low cell dose infused. Both related and unrelated cord blood transplants have been performed with high rates of success for a variety of h...

OBJECTIVE To investigate the cost-effectiveness of private umbilical cord blood banking. METHODS A decision-analytic model was designed comparing private umbilical cord blood banking with no umbilical cord blood banking. Baseline assumptions included a cost of $3,620 for umbilical cord blood banking and storage for 20 years, a 0.04% chance of requiring an autologous stem cell transplant, a 0....

BACKGROUND Umbilical cord banks are a central component, as umbilical cord tissue providers, in both medical treatment and scientific research with stem cells. But, whereas the creation of umbilical cord banks is seen as successful practice, it is perceived as a risky style of play by others. This article examines and discusses the ethical, medical and legal considerations that arise from the o...

 Feto-placental infection or placentitis of unidentified etiology--34%. Of these, 17.8% were associated with bacterial infection.  Complications during birth--19%  Congenital anomalies including contracted foals--10%  No diagnosis--17%  Other causes included placental edema, premature placental separation, twins, umbilical cord anomalies, placental villous atrophy, body pregnancy, fetal di...

The Stillbirth Collaborative Research Network recently reported on the probable or possible cause of death of 512 stillbirths whose mothers consented to complete postmortem examination [1]. Umbilical cord accidents (UCA) represented 10% of stillbirths [1]. In Caucasians the UCA associated stillbirth rate was 13% and 4% in non-Hispanic black. 9% of stillbirths were due to hypertension and 8% due...