Uveal melanoma (UM) is the most prevalent intraocular malignant tumor in the Western world. The prognosis of survival in the presence of metastatic disease is 2-7 months, depending on the treatment applied. - This article presents a case of metastatic UM with successful complex treatment of liver metastases. - A 49-year old female, underwent removal of the right eyeball in 1996 due to a histolo...

Within the framework of two phase III clinical trials, the superior results of concomitant chemotherapy and radiotherapy in the treatment of patients with locally advanced anal carcinoma were demonstrated. A further phase III clinical trial showed that the role of mitomycin C as part of the concomitant chemotherapy in combination with 5-fluorouracil appeared to be essential in obtaining a highe...

Although in centers where pancreatectomy is performed frequently, associated morbidity and mortality rates have improved, long-term outcomes in pancreatic adenocarcinoma patients remain poor when surgery is the sole therapeutic modality. The impact of adjuvant chemotherapy on survival in patients with localized pancreatic cancer remains incompletely defined. The European Study Group for Pancrea...

As a first step of treatment of landfill leachates (total COD – 1,430-3,810 mg/l, total nitrogen 90162 mg/l), a performance of laboratory UASB reactors has been investigated under mesophilic (30 C), sub-mesophilic (20 C) and psychrophilic (10 C) conditions. Under hydraulic retention times (HRT) of around 7 h, when the average organic loading rates (OLR) were around 5 g COD/l/day, the total COD ...

PURPOSE The purpose of this study was to describe a combination treatment for choroidal neovascular (CNV) membrane, secondary to punctate inner choroidopathy (PIC). PATIENT AND METHODS A 44-year-old female patient was diagnosed with PIC complicated by the development of recurrent juxtafoveal neovascular membrane. The treatment included a sequence of monotherapy regimens: systemic steroid ther...

Thirty-seven severely-disabled agoraphobics were randomly assigned to (1) Imipramine-no exposure. (2) Imipramine + exposure or (3) Placebo + exposure groups. To provide a more stringent test of the pharmacological effects of imipramine independent of exposure to phobic stimuli, Ss in the Imipramine-no exposure condition received antiexposure instructions during the first 8 weeks of therapy. Ass...

background : functional dyspepsia is considered one of the most common digestive diseases with tremendous cost and time expenditures for patients and health systems. an increase in the numbers of inflammatory cells such as mast cells and eosinophils are reported in the gastrointestinal mucosa of these patients. this study aims to determine the effects of histaminic receptor blockage on patients...

the treatment of juxtapapillary retinal capillary hemangiomas (jrchs) is still a therapeutic dilemma without established guidelines. because of the location of these hemangiomas on or adjacent to the optic nerve, treatment is difficult and complex, especially when jrchs are located in the papillomacular bundle. this manuscript reviews the clinically relevant data on literature regarding the tre...