A novel electrochemical (EC) method for fast and efficient reduction of the disulfide bonds in proteins and peptides is presented. The method does not use any chemical agents and is purely instrumental. To demonstrate the performance of the EC reactor cell online with electrospray mass spectrometry, insulin and somatostatin were used as model compounds. Efficient reduction is achieved in contin...

This paper presents experimental results of a coverage analysis in a WCDMA network using the 850 MHz band; an urban electromagnetic propagation environment is considered. Obtained coverage estimation maps are based on Krige statistical method of interpolation. Key performance parameters used in this work are the CPICH and Ec. The results could be used to identify problems and help to optimize c...

UNLABELLED Endometrial cancer (EC) is the second most common malignancy associated with hereditary non-polyposis colorectal cancer (HNPCC) family. The development of HNPCC is associated with defects in DNA mismatch repair (MMR) pathway resulting in microsatellite instability (MSI). MSI is present in a greater number of EC than can be accounted for by inherited MMR mutations, therefore alternati...

BACKGROUND The significant role of retail poultry meat as an important exposure pathway for the acquisition and transmission of extended spectrum β-lactamase-producing Escherichia coli (ESBL-EC) into the human population warrants understanding concerning those operational practices associated with dissemination of ESBL-EC in poultry meat retailing. Hence, the objective of this study was to dete...

The present study examined the direct and indirect relations of family contextual factors, effortful control (EC), and the early math and English literacy skills of first and second-generation Chinese American immigrant children in early elementary school. Using a socioeconomically diverse sample of 258 Chinese American children (53% receiving freeor reduced-price school lunch), we assessed EC ...

Detection of Alzheimer's disease (AD) at the first stages of the pathology is an important task to accelerate the development of new therapies and improve treatment. Compared to AD detection, the prediction of AD using structural MRI at the mild cognitive impairment (MCI) or pre-MCI stage is more complex because the associated anatomical changes are more subtle. In this study, we analyzed the c...

Current treatments for esophageal cancer (EC) rely on tumor eradication by surgery or chemoradiotherapy. However, such treatments do not account for the assessment and adjustment of the immune status of the patients. Regulatory B cells (Bregs) have been confirmed as a negative regulatory subtype in B‑cell populations. However, to the best of our knowledge, there have been no direct studies on B...

Absorption of orally administered (0)-epicatechin (EC) in rats was studied to obtain plasma pharmacokinetic profiles of EC metabolites. Rats were administered 172 mmol/kg body weight of EC, and blood was collected from the tail for 8 h after administration. Seven groups of compounds possessing the basic structure of EC were identified by using a combination of enzymatic hydrolysis, HPLC and ele...

The effectiveness of a hybrid approach comprising electrocoagulation (EC) and adsorption (AD) (using natural zeolite and/or palygorskite) processes to treat raw sanitary landfill leachate (SLL) was investigated in terms color, dissolved chemical oxygen demand (d-COD), nitrate nitrogen (NO3−-N) ammonium (NH4+-N) removal. Optimal EC conditions were found with current density 30 mA cm−2, Fe electr...