نتایج جستجو برای: colorectal cancer

تعداد نتایج: 925796  

Journal: :gastroenterology and hepatology from bed to bench 0
atena irani shemirani mahdi montazer haghighi phd saman milanizadeh mohammad yaghoob taleghani seyed reza fatemi behzad damavand

aim : the aim of the current investigation was to examine the profile of kras mutations accompanied with msi (microsattelite instability) status in polyps and colorectal carcinoma tissues in an iranian population. background : kras mutations in colorectal cancer cause resistance to anti-epidermal growth factor receptor (egfr). so it can be considered as a true indicator of egfr pathway activati...

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Journal: :caspian journal of internal medicine 0
dariush moslemi division of radiation oncology, school of medicine, babol university of medical sciences, babol, iran mohammad mohammadianpanah colorectal research center, shiraz university of medical sciences, 71936, shiraz, ir iran.

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Journal: مجله پزشکی ارومیه 2019
Abdurrahman Charkazi, Aiuob sofizadeh, Ehsan Allah Kalteh, fatemeh karimi, Noureddin Niknam, Vahid bay,

Background & Aims: The burden of premature mortality is used to prioritize health problems. The purpose of this study was to estimate the burden of premature mortality due to colorectal cancer in Golestan from 2011 – 2015. Materials & Methods: In this sequential cross-sectional study, based on the province mortality registration data and standard expected years of life lost (SEYLL), the burden...

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ژورنال: مجله اپیدمیولوژی ایران 2021
Hanafi Bojd , AA, Holakoui-Naeini , K, Nematollahi, SH, Ostadghaderi, M,

Background and Objectives: The incidence of colorectal cancer has increased significantly in Iran in recent decades. The pattern of occurrence varies in different populations. A study was conducted to perform a spatial analysis of colorectal cancer and some of its risk factors in Iran using GIS.   Methods: The data of this descriptive-analytic study included colorectal cancer incidence as a d...

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Journal: :international journal of epidemiologic research 2015
parisa chamanparaa abbas moghimbeigi javad faradmal jalal poorolajal

background and aims: the aim of this study was the modeling of the incidence rates of colorectal, breast and prostate cancers using a shared component model in order to explore the spatial pattern of their shared risk factors (i.e., obesity and low physical activity) affecting on cancer incidence, and also to estimate the relative weight of these shared components. methods: in this study, the ...

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Journal: :iranian biomedical journal 0
احسان خداپسند ehsan khodapasand نرگس جعفرزاده narges jafarzadeh فرید فرخی farid farrokhi بهنام کمالی دهقان behnam kamalidehghan مسعود هوشمند massoud houshmand

background: bax and bcl-2 are the major members of bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. methods: in this study, the relative level of mrna expression of bax and bcl-2 genes was deter...

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Journal: :گوارش 0
parvin mehdipour morteza atri saeed hashemi hiyam nassarizadeh gholamreza tavousi seyed saeed hoseini asl

cancer-genetics epidemiology and genetics investigation in colorectal carcinomas: directions towards prevention

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Journal: :iranian journal of cancer prevention 0
alireza abadi dept. of community medicine and health, shahid beheshti university of medical sciences, tehran, iran farzaneh ahmadi dept. of biostatistics, school of paramedical, shahid beheshti university of medical sciences, tehran, iran hamaid alavi majd dept. of biostatistics, school of paramedical, shahid beheshti university of medical sciences, tehran, iran mohammad esmaeil akbari cancer research center, shahid beheshti university of medical sciences, tehran, iran zainab abolfazli khonbi dept. of english language, kashan university of medical sciences, kashan, iran esmat davoudi monfared dept. of community medicine and health, shahid beheshti university of medical sciences, tehran, iran

background: colon cancer is the third cause of cancer deaths. although colon cancer survival time has increased in recent years, the mortality rate is still high. the cox model is the most common regression model often used in medical research in survival analysis, but most of the time the effect of at least one of the independent factors changes over time, so the model cannot be used. in the c...

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Journal: :گوارش 0
maryam momeni atefe ghanbari

background: â  colorectal cancer (crc) is one of the most common invasive cancers responsible for physical and psychosocial morbidity. therefore, quality of life (qol) is an important outcome for these patients. despite advances in understanding qol, the majority of available research is from urban areas. the present study aims to compare qol between urban and rural crc patients. â  materials a...

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Journal: :research in pharmaceutical sciences 0
somayeh atari-hajipirloo 1department of biochemistry , student research committee,urmia university of medical sciences, urmia, i.r. iran. saba nikanfar 2department of biochemistry, urmia university of medical sciences, urmia, i.r. iran. amir heydari 3department of pharmacology, cellular and molecular research center, urmia university of medical sciences, urmia, i.r. iran. fatemeh kheradmand 4department of clinicalbiochemistry, cellular and molecular and solid tumor research center, urmia university of medical sciences, urmia, i.r. iran.

mono-targeting by imatinib as a main antitumor agent does not always accomplish complete cancer suppression. 2,5-dimethyl-celecoxib (dmc) is a close structural analog of the selective cyclooxygenase-2 (cox-2) inhibitor, celecoxib, that lacks cox-2 inhibitory function. in this study, we aimed to show the apoptotic effects of imatinib in combination with dmc in human ht-29 colorectal cancer (crc)...

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