Metallosis of the hip is usually defined as aseptic fibrosis, local necrosis, or loosening of the prosthesis secondary to metallic corrosion and release of wear debris.8 It has also been defined as gray discoloration of the tissues of the joint, pain, an effusion, and elevated serum metal levels. Metallosis has been found with stainless steel, titanium, and cobalt chromium alloy femoral prosthe...

574 www.thelancet.com Vol 383 February 8, 2014 In May, 2012, a 55-year-old man was referred to our clinic for severe heart failure (New York Heart Association class IV). He had raised brain natriuretic peptide of 1053 ng/L (normal <55 ng/L) and his estimated ejection fraction by echocardiography was 25%. His medical history was mostly uneventful, apart from the fact that he had had both hips re...

In this study, magnesium is alloyed with varying amounts of the ferromagnetic alloying element cobalt in order to obtain lightweight load-sensitive materials with sensory properties which allow an online-monitoring of mechanical forces applied to components made from Mg-Co alloys. An optimized casting process with the use of extruded Mg-Co powder rods is utilized which enables the production of...

and porcelain-fused-to-metal restorations instead of gold or silver alloys. This tendency seems to be the same a]1 over the world, However, the expanded use of nickel-containing base metal alloys in dentistry has raised questions concerning their biological s fety, namely, carcinogenic and sensitivity risks.i) On the other hand, since pure titanium or titanium-based alloys have excellent biocom...

Introduction: Bearing couples within total ankle arthroplasty (TAA) typically utilize cobalt chromium alloys articulating on ultrahigh molecular weight polyethylene (UHMWPE). Articulation of these surfaces during in vivo loading can generate UHMWPE wear particles, which may then result in osteolysis and component loosening [1]. Osteolysis has been observed following TAA in 15-22% of patient pop...

BACKGROUND There were at least 31,171 metal-on-metal (MoM) hip implants in the UK between 2003 and 2011. Some of these were subject to failure and widescale recalls and revisions followed. METHOD This is a presentation of ten cases (mean age 60 years) where we evaluated neuropsychiatric morbidity following metal-on-metal hip implant failure and revision. Implants were ASR total hip replacemen...

BACKGROUND In-stent restenosis (ISR) is the major limitation of percutaneous coronary stenting procedure. The elements like nickel, chromate and molybdenum are known to cause contact allergy. Hypersensitivity reaction, against these metal ions, may be one of the reasons of ISR. Cobalt chromium coronary stents, which are increasingly being used in percutaneous coronary interventions, have more n...

We investigated the relationship between the toxic effects of metal wear particles and their ability to stimulate the release of inflammatory mediators implicated in bone resorption. In vitro studies were carried out with use of rat peritoneal macrophages, which were exposed to either cobalt-chromium-alloy or titanium-aluminum-vanadium particles, milled from the metal components of hip prosthes...

BACKGROUND Adverse Reaction to Metal Debris (ARMD) is still a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. ARMD consists of a wide range of alterations in periprosthetic tissues, most important of which are metallosis, inflammation, pseudotumors and necrosis. Studies investigating histopathological findings and their association to implant wear or ...

The effect of additions of tantalum (Ta) to a 40-30-30 cobalt (Co) -chromium (Cr) nickel (Ni) alloy has been studied for several years at the University of Michigan. Mechanical properties of a series of these alloys have been reported by Mohammed and Asgar.1 Those results showed that an alloy containing 13% Ta would have an ultimate tensile strength of 124,000 psi, a yield strength of 90,000 ps...