Phylogenetic relationships and genetic variation between two Iranian sheep breeds were analyzed using cytochrome b (cyt-b) gene sequences. The genomic DNA was isolated by salting out method and amplified cytochrome b gene using polymerase chain reaction restriction (PCR) method with a pair of primer. A partial sequence of cyt-b gene of Iranian sheep is 780 bp and contained 13 variable sites and...

Monocytes fundamentally contribute to immune surveillance and the inflammatory response in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site of injury requires their trafficking across the blood vessel wall. A series of events, including capture, rolling, slow rolling, arrest, adhesion strengthening, and lateral locomotion, precede monocyte transmigration....

Hu5F9-G4 and AK117, novel cluster of differentiation 47 blockers, are used to treat solid tumors hematoma. Because is expressed on erythrocytes, treatment with monoclonal anti-cluster may interfere the results transfusion compatibility testing. This study analyzed interference AK117 Saline microcolumn gel methods were identify blood types patients. To screen irregular antibodies, salt water, in...

Homeobox transcription factors exert essential roles in embryogenesis and are thought to govern regenerative cell differentiation. In this issue of Cell, MacLean and colleagues (MacLean et al., 2005) describe a new homeobox gene cluster composed of genes selectively expressed in reproductive tissues. Remarkably, the cluster is on the X chromosome, and the genes display a colinear pattern of exp...

Lutzomyia longipalpis, a sibling complex, is the main vector of Leishmania chagasi/infantum. Discriminating between siblings is important as they may differ in vectorial capacity. Lutzomyia longipalpis populations display distinct male sex pheromone chemotypes. We investigated the phylogeographic pattern of variation at microsatellite loci from 11 populations from Brazil and Venezuela related t...

The switch from transcriptionally activating MYC-MAX to transcriptionally repressing MAD1-MAX protein heterodimers has been correlated with the initiation of terminal differentiation in many cell types. To investigate the function of MAD1-MAX dimers during differentiation, we disrupted the Mad1 gene by homologous recombination in mice. Analysis of hematopoietic differentiation in homozygous mut...

targeted extension for heterogeneous farming systems is a challenge in developing countries. farm type identification and characterization based on estimates of income from different farm components allows simplifying diversity in farming systems. use of multivariate statistical techniques, such as principal component analysis (pca) and cluster analysis (ca), help in such farm typology delineat...

Morphology and distribution of melanocytes are critical imaging information for the diagnosis of melanocytic lesions. However, how to image intratumoral melanocytes noninvasively in pigmented skin tumors is seldom investigated. Third-harmonic generation (THG) is shown to be enhanced by melanin, whereas high accuracy has been demonstrated using THG microscopy for in vivo differential diagnosis o...