background: for more than four decades clomiphene citrate has been the first line of the treatment for ovulatory disorders. the aim of this study was to compare the effects of letrozole and clomiphene citrate on ovulation and pregnancy rate in patients with polycystic ovary syndrome.   methods: in this prospective double-blind study, 100 patients with polycystic ovary syndrome were randomized i...

background:   objective: to evaluate the relative efficacy of lod and gonadotropins for infertile women with clomiphene citrate- resistant poly cystic ovary syndrome (pcos).   materials and methods: a complete electronic literature search in databases including embase, medline, cochrane library and google scholar for some specific keywords was accomplished. we contained randomized clinical tria...

This paper is based on a Cochrane review published in The Cochrane Library, issue 2, 2001 (see www.CochraneLibrary. net for information) with permission from The Cochrane Collaboration and Update Software. Cochrane reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and The Cochrane Library should be consulted for the most recent version of the revi...

BACKGROUND Chromium picolinate could be effective in clomiphen citrate resistant PCOS patients. OBJECTIVE To compare the effects of chromium picolinate vs. metformin in clomiphen citrate resistant PCOS patients. MATERIALS AND METHODS The present randomized clinical trial was performed on 92 women with clomiphen citrate-resistant PCOS at the clinics which were affiliated to Shiraz University...

In diabetic patients, euglycaemia at the time of conception is crucial for the success of the pregnancy. In consideration of the difficulty in achieving and maintaining tight glycaemic control for long periods, we administered clomiphene citrate, which is usually indicated in cases of absent or infrequent ovulation, to enhance fecundability in 10 pregestational diabetic patients. All conceived ...

We present ovulation that occurred after the administration of traditional Chinese herbal medicine for 3 months in a woman with premature ovarian failure (POF) and secondary amenorrhea for 8 years. Traditional Chinese medicine concentrated herbal extracts of cooked rehmannia, Chinese yam, wolfberry fruit, dogwood fruit, cyathula root, dodder seed, antler glue, tortoise-plastron glue, epimedium ...

Background: Clomiphene Citrate is composed of two structural isomers: cisor Zuclomiphene citrate (Zu) and transor Enclomiphene citrate (En). Clomiphene, as well as isolate isomers, has recently been shown to have effects on Ebola virus infections. It has been shown that the enclomiphene molecule is an estrogen antagonist and that zuclomiphene is inactive. We demonstrate here that the two isomer...