Currently, the use of blood irradiation for inactivating pathogenic microbes in infected blood products and preventing graft-versus-host disease (GVHD) in immune suppressed patients is greater than ever before. In these systems, dose distribution and uniformity are two important concepts that should be checked. In this study, dosimetry of the gamma chamber blood irradiator model Gammacell 3000 ...

The manuscripts included in this special issue of Cancer Biotherapy & Radiopharmaceuticals highlight current data and theoretical foundations regarding dose–response relationships related to radionuclide therapy kidney toxicity. With the use of the kidney dosimetry model presented in MIRD 19,1 these experimental and clinical data, when correlated with accurate regional dose information, may pro...

Background All randomised phase 3 studies of selective internal radiation therapy for advanced hepatocellular carcinoma published to date have reported negative results. However, these did not use personalised dosimetry. We aimed compare the efficacy a versus standard dosimetry approach with yttrium-90-loaded glass microspheres in patients carcinoma. Methods DOSISPHERE-01 was randomised, multic...

The goal of Task Group 25 (TG-25) of the Radiation Therapy Committee of the American Association of.Physicists in Medicine (AAPM) was to provide a methodology and set of procedures for a medical physicist performing clinical electron beam dosimetry in the nominal energy range of 5-25 MeV. Specifically, the task group recommended procedures for acquiring basic information required for acceptance...

PurposePatient-specific dosimetry in MRT relies on quantitative imaging, pharmacokinetic assessment and absorbed dose calculation. The DosiTest project was initiated to evaluate the uncertainties associated with each step of clinical workflow through a virtual multicentric trial. This work presents generation simulated SPECT datasets based GATE Monte Carlo modelling its corresponding experiment...

normal 0 false false false en-us x-none fa introduction: in radiation therapy centers across iran, protection of normal tissues is usually accomplished by either cerrobend or lead block shielding. in this study, the influence of these two shielding methods on central axis dose distribution of photon beam a cobalt unit was investigated in clinical conditions. materials and methods: all measureme...

Computed tomography (CT)/magnetic resonance imaging (MRI) fusion is considered to be the best method for postimplant dosimetry of permanent prostate brachytherapy; however, it is inconvenient and costly. In T2*-weighted image (T2*-WI), seeds can be easily detected without the use of an intravenous contrast material. We present a novel method for postimplant dosimetry using T2*-WI/T2-weighted im...

Light dosimetry is an important parameter that affects the efficacy of photodynamic therapy (PDT). However, the irregular morphologies of lesions complicate lesion segmentation and light irradiance adjustment. Therefore, this study developed an illumination demo system comprising a camera, a digital projector, and a computing unit to solve these problems. A three-dimensional model of a lesion w...

A survey of the literature was conducted to establish the anticipated ranges of exposure to both physicians and patients during cardiac catheterization. A brief explanation of a technic for using time-lapse photography and a computer model for exposure calculation is presented. The thermoluminescent dosimeter (TLD) results used as controls for exposure values calculated by the developed techniq...

introduction: in radiotherapy, methods of treatment planning are becoming increasingly more complicated. this requires verification of the doses delivered to increasingly smaller and more precise regions. radiotherapy techniques are continuously employing smaller and smaller field sizes to deliver tighter radiation doses with higher therapeutic ratios, generating interest among researchers to p...