Expression of the K1 gene of human herpesvirus 8 activates nuclear factor-kappaB and induces lymph node hyperplasia and lymphomas in transgenic mice. To further delineate its role in cell survival, we determined whether K1 altered apoptosis of lymphoma cells. K1 protein is expressed in Kaposi sarcoma and primary effusion lymphoma. We retrovirally transfected BJAB lymphoma, THP-1, U937, and Kapo...

primary hepatic lymphoma (phl) is rare and possibly associated with viral hepatitis and autoimmune diseases. scleroderma could exceptionally be complicated by lymphoma. we describe phl occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. ct scan, performed to work-up abdominal discomfort, constipation, and ele...

  Primary Hepatic Lymphoma (PHL) is rare and possibly associated with viral hepatitis and autoimmune diseases. Scleroderma could exceptionally be complicated by lymphoma. We describe PHL occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. CT scan, performed to work-up abdominal discomfort, constipation, and ...

We reported recently that medium conditioned with mouse lung microvessel endothelial cells possessed chemotactic activity for a highly lung-metastatic variant (L17) of the RAW117 murine large-cell lymphoma cell line but not for the poorly metastatic parental cells (P) or a liver-metastasizing variant (H10). The chemotactic factor was purified to homogeneity by a five-step procedure involving hy...

AIM To examine the effects of echinomycin, a compound that inhibits DNA-binding activity of hypoxia-inducible factor-1 (HIF1), on leukaemia cell growth. MATERIALS AND METHODS Three acute myeloid leukaemia cell lines and three T-lymphoblastic leukaemia cell lines were cultured with echinomycin. Cell growth, mRNA and protein expression levels were examined by WST-1 assay, reverse-transcription ...

A 66-year-old man presented with a white blood cell count of 62.63 10 /L. Peripheral blood (PB) smear showed 80% smallto medium-sized atypical lymphoid cells with irregular to cleaved (panel A; original magnification 3500, Wright-Giemsa stain) or binucleated nuclear contours, and slightly condensed chromatin (panel B; original magnification 31000, Wright-Giemsa stain). Bone marrow (BM) aspirate...

We used mRNA from a mutant S49 mouse lymphoma cell line that produces ornithine decarboxylase (OrnDCase) as its major protein product to synthesize and clone cDNA. Plasmids containing OrnDCase cDNA were identified by hybrid selection of OrnDCase mRNA and in vitro translation. The two of these with the largest inserts together span 2.05 kilobases of cDNA. Southern blot analysis of DNA from wild-...

Primary testicular lymphoma (PTL) is a rare form of extranodal lymphoma, this neoplasm the most common malignant tumor testis in elderly age, and majority cases are histologically diffuse large B-cell (DLBCL), accounting for 80% to 98% non-hodgkin lymphoma. Patients with primary DLBCL show continuously high risk recurrence no plateau survival curves tendency involve other sites, especially cent...

Relevance. Ageing is an important factor causing various diseases and functional failure. markers help to characterize the ageing process comprehensively. Currently, molecular genetic human are most promising (Molecular / DNA-Based Markers).The study aimed identify relationship between age-related dental syndromes some oral predictors of ageing. Materials methods. The included 200 elderly patie...

We studied flow cytometry in 156 fine-needle aspirations (FNAs) of lymph nodes performed between June 1993 and September 1998. Information from flow cytometry was combined with cytomorphologic evaluation, and the diagnosis determined by using combined modalities was compared with tissue biopsy results or clinical follow-up. In 74 cases, a combined cytopathologic-flow cytometric diagnosis of lym...