A multidetector row computed tomography (MDCT) image is being considered as a possible alternative to current imaging methods for evaluating vessel anatomy and morphology of atherosclerotic plaques in variety arterial beds. It evaluate the entire vasculature using MDCT. Furthermore, MDCT capable visualizing wall quantifying calcified noncalcified plaques. In total, 72 patients (56.9% male 43.1%...

BACKGROUND Carotid atherosclerosis and aortic atherosclerosis are both associated with coronary artery disease and cerebral thromboembolism. However, the relationship between asymptomatic carotid and aortic atherosclerosis is not well known. METHODS AND RESULTS Sixty-two consecutive cardiac patients (mean age 57 years) without a history of atherosclerotic cardiovascular disease who were refer...

A review of the predictive ability of arterial and valvular calcification has shown an additive effect of calcification in more than 1 location in predicting mortality and coronary heart disease, with mitral annual calcification being a particularly strong predictor. In individual arteries and valves there is a clear association between calcification presence, extent and progression and future ...

The phage enzymes can lyse the host in which they resides, but it is not yet known whether they show any effect on the non-susceptible hosts on solid media (Consortia). It is observed during our studies that the consortial lawn on the solid medium shows clear plaques irrespective of their specificity to the inoculated phages. The consortial studies indicate the combined application of phage enz...

The classic plaque assay is a method for counting infectious viral particles, however its complexity limits its use in a variety of virological experiments. To simplify the operation and to improve the repeatability, we employed an improved plaque assay procedure based on Avicel to make the whole experiment easier and optimize the results on a model of Vero cells infection with Enterovirus 71(E...

IntroductIon Psoriasis is characterized by raised, scaly, well‐demarcated, erythematous oval plaques.[1] Although studies have revealed that disruption of immune tolerance and excessive production of inflammatory factors play important roles in the pathogenesis of psoriasis, the exact mechanism is still not clear.[2] Previous studies have shown that the concordance rate of monozygotic twins wit...

ver since Anitschkow’s pioneering experiments on the role f cholesterol in the causation of atherosclerotic plaques in abbits (2), this intriguing molecule has been at the heart of ebate and controversy (3). Initially, the total cholesterol evel was used as a measure of risk, then a distinction etween and -lipoproteins emerged. As the role of pecific lipoproteins became clear, attention focused...

The genus Naegleria comprises of free living ameboflagellates found in soil and fresh water. More than 30 species have been isolated but only N. fowleri has been associated with human disease. N. fowleri causes primary amoebic meningoencephalitis (PAM), an acute, often fulminant infection of CNS. Here we report a rare and first case of PAM in an immunocompetent elderly patient from this part of...

•Primary vaginal clear cell adenocarcinoma (PVCCA) coexists with urinary tract anomalies without exposure to diethylstilbestrol in some cases.•PVCCA in our case showed genetic alterations of well-known cancer related genes, including a mutation of PIK3CA.•The genetic profile suggests that the carcinogenesis of PVCCA might have elements common with that of OCCA.

Alzheimer's disease and Parkinson's disease are the most common neurodegenerative disorders of the human brain. They are characterized by the presence of ordered filamentous assemblies which gradually develop in a small number of nerve cell types. I n Alzheimer's disease, vulnerable nerve cells develop neurofibrillary tangles, neuropil threads and abnormal neurites, whereas in Parkinson's disea...