BACKGROUND AND PURPOSE The high-fat, low-carbohydrate ketogenic diet (KD) is effective in many cases of drug-resistant epilepsy, particularly in children. In the classic KD, fats consist primarily of long-chain saturated triglycerides. Polyunsaturated fatty acids (PUFAs), especially the n-3 type, decrease neuronal excitability and provide neuroprotection; pilot human studies have raised the pos...

Background: Refractory (intractable/pharmaco-resistant) epilepsy in children is considered if disabling seizures continue despite appropriate trials of two anti-seizure drugs, either alone or combination. Ketogenic diets are used as a treatment option many countries for with refractory seizures; however, few patients have tried it Saudi Arabia. Therefore, we examined the relationship between ex...

Ketogenic diet is used in weight control. This study aimed at finding out exposure, perception and working-class adult females’ response to information. The specific objectives are: To examine the exposure level of adults Awka Anambra state ketogenic information, determine how they perceive finally, females respond was designed as a survey. Using an online sample size calculator, 384 civil serv...

BACKGROUND The ketogenic diet is an effective non-pharmacologic treatment for medically resistant epilepsy. The aim of this study was to identify any predictors that may influence the response of ketogenic diet. METHODS A retrospective chart review for all patients with medically resistant epilepsy was performed at a tertiary care epilepsy center from 1996 to 2012. Patient- and diet-related v...

Alzheimer's disease is a currently incurable neurodegenerative disease affecting millions of individuals worldwide. Risk factors for Alzheimer's disease include genetic risk factors, such as possession of ε4 allele of apolipoprotein E (ApoE4) over the risk-neutral ApoE3 allele, and lifestyle risk factors, such as diet and exercise. The intersection of these two sources of disease risk is not we...

PURPOSE To examine the process for transitioning adolescents on dietary management for intractable epilepsy to adult neurologic care. METHODS Ten patients, ages 6-16 years when the ketogenic or modified Atkins diet was initiated, were identified; age at transition was 18-43 years. All patients were seen at Johns Hopkins Hospital, Baltimore, Maryland. RESULTS Seven remain on diets (4 Ketogen...