Ginsenoside metabolite compound K (CK) is a metabolite of ginsenoside, and belongs to dammarane-type triterpene saponins according to its structure. It has been reported that CK exerts anti-inflammatory activity. Our previous studies showed that CK alleviated adjuvant-induced arthritis (AA) and collagen-induced arthritis (CIA) via suppressing T cell activation. Our recent study showed that the ...

BACKGROUND Creatine kinase-MB (CK-MB) elevation after percutaneous coronary intervention (PCI) has been associated with increased risk for mortality. Although most studies have defined periprocedural myocardial infarction (pMI) as an elevation in CK-MB >3× upper limit of normal (ULN), use of different CK-MB assays and variation in site-specific definitions of the ULN may limit the value of such...

Ginsenosides are triterpenoids that are found in P. ginseng; they have numerous important structural, functional and pharmacological properties. In this work, a desolvation method was used to entrap ginsenoside CK within bovine serum albumin (BSA) to form BSA–CK nanoparticles (NPs), which enhance its aqueous solubility and stability. Following purification, the BSA–CK NPs were characterized by ...

OBJECTIVES The study evaluated the incidence and predictors of creatine kinase-MB isoenzyme (CK-MB) elevation after successful coronary intervention using current devices, and assessed the influence on in-hospital course and midterm survival. BACKGROUND The CK-MB elevation after coronary intervention predominantly using balloon angioplasty correlates with late cardiac events of myocardial inf...

Cops and Robbers is a pursuit and evasion game played on graphs that has received much attention. We consider an extension of Cops and Robbers, distance k Cops and Robbers, where the cops win if at least one of them is of distance at most k from the robber in G. The cop number of a graph G is the minimum number of cops needed to capture the robber in G. The distance k analogue of the cop number...

BACKGROUND Many studies have used creatinine kinase (CK), myocardial bound for CK (CK-MB), and cardiac troponin I (cTnI) and T (cTnT) to evaluate myocardial cells injury after ablation. We applied measurements of the blood concentration of cardio-specific biomarkers as surrogates for the injured cell mass. AIM To clarify which of the standard biomarkers are useful in the evaluation and quanti...

We examined the clinical and analytical performance of two immunoassays (Becton Dickinson CK-MB; Ciba-Corning Magic Lite CK-MB) in which monoclonal anti-CK-MB antibodies are used for directly measuring creatine kinase (EC 2.7.3.2) isoenzyme MB (CK-MB) in serum, and also one electrophoretic method (Ciba-Corning). Within- and between-assay precision for both immunoassays was good at the upper ref...

The rates of degradation of creatine kinase subunits, M-CK and B-CK subunits, were measured in cultured myogenic cells and in subcultured fibroblasts. In differentiated myogenic cells, the myotubes, both M-CK and B-CK subunits are synthesized. Their rates of degradation were compared. The M-CK subunits is slightly more stable and is degraded with an average apparent half-life of 75 h, whereas t...