Serum and urinary electrolytes were estimated in 33 patients with hepatitis and 35 with cirrhosis. Forty two percent patients with hepatitis and 46% with cirrhosis bad hyponatraemia while 30% with hepatitis and 37% with cirrhosis had low serum potassium levels. Low urinary sodium was found in 27.3% cases of hepatitis and 40% cirrhotics and low urinary potassium in 21.2% and 45.7% cases of hepat...

aim : this study evaluated the association between serum endothelin- 1 level and symptoms, clinical examination, laboratory and cardio-respiratory parameters, in patients with cirrhosis compared to controls. background : cirrhosis is associated with significant portal, pulmonary and systemic vascular abnormities. recent studies have suggested that endothelin -1 may have a significant role in th...

BACKGROUND Liver cirrhosis is a large burden on global health, causing over one million deaths per year. Observational studies have reported an inverse association between coffee and cirrhosis. AIMS To perform a systematic review and meta-analysis to characterise the relationship between coffee consumption and cirrhosis. METHODS We searched for studies published until July 2015 that reporte...

Aim Insulin-like growth factor 1 (IGF-1), which is primarily produced in hepatocytes and associated with liver functional reserve, plays a crucial role the pathological condition of cirrhosis. This study aimed to investigate usefulness serum IGF-1 levels for predicting long-term prognosis decompensation development patients Methods We retrospectively evaluated 148 cirrhosis divided them into th...

BACKGROUND Liver cirrhosis is a major yet largely preventable and underappreciated cause of global health loss. Variations in cirrhosis mortality at the country level reflect differences in prevalence of risk factors such as alcohol use and hepatitis B and C infection. We estimated annual age-specific mortality from liver cirrhosis in 187 countries between 1980 and 2010. METHODS We systematic...

Hepatitis B and hepatitis C are leading causes of chronic liver disease, particularly cirrhosis. Recently, several studies have observed that statins have an inverse relationship with cirrhosis in hepatitis B or C patients. However, no published meta-analysis studied the protective effect of statins on cirrhosis. Thus, we conducted a systematic review and meta-analysis of published observationa...

BACKGROUND Although chronic alcohol intake and chronic hepatitis C may progress to cirrhosis and hepatocellular carcinoma (HCC), few data are available about survival and probability of developing HCC in decompensated cirrhosis of both aetiologies. METHODS This study identified factors related with probability of developing HCC and survival in a cohort of 377 consecutive patients with decompe...

Chronic hepatitis C is often asymptomatic, at least during the first decade following hematopoietic stem cell transplantation. Progression to advanced liver disease or cirrhosis in patients surviving more than 10 years is currently thought to be rare. Among 1078 patients who underwent an allogeneic transplantation between January 1973 and January 1995, 96 patients infected by hepatitis C virus ...

Unsafe use of alcohol results in approximately 2.5 million deaths worldwide, with cirrhosis contributing to 16.6% of reported deaths. Serum insulin levels are often elevated in alcoholism and may result in diabetes, which is why alcoholic liver disease and diabetes often are present together. Because there is a sizable population with these diseases alone or in combination, the purpose of this ...

OBJECTIVE Chronic synovial inflammation causes primary osteoarthritis, but it is unknown whether chronic systemic inflammation does, too. Patients with cirrhosis have chronic systemic inflammation and therefore we examined the association between cirrhosis and primary osteoarthritis of the hip and knee. METHODS In Danish healthcare databases we identified all residents over 60 years diagnosed...