The role of the suprachiasmatic nuclei (SCN) in generating circadian rhythms in physiology and behavior is well established. Recent evidence based on clock gene expression indicates that the rodent SCN are composed of at least two functional subdivisions. In Syrian hamsters (Mesocricetus auratus), cells in a subregion of the caudal SCN marked by calbindin-D(28K) (CalB) express light-induced, bu...

Several geometric, graph theoretical and combinatorial techniques useful for the teaching, analysis, generation and automated recognition of rhythms are proposed and investigated. The techniques are illustrated on the six fundamental 4/4 time clave and bell rhythm timelines most frequently used in African, Brazilian and Cuban music. It was found that Pressing's measure of rhythm complexity agre...

Photic information transmitted from the eyes to the suprachiasmatic nucleus (SCN) is essential for entrainment of circadian behavioral and physiological rhythms in mammals. Under conditions of constant darkness, these rhythms are maintained by the circadian pacemaker cells of the SCN [Bioessays 22 (2000) 23]. It is possible, however, that even in the absence of light, the eyes, which also conta...

Nature is full of nonlinearities, responsible for a great variety of responses in natural systems. Physiological rhythms constitute a central characteristic of life, which is motivating the analysis of dynamical aspects related to natural systems. Natural rhythms could be either periodic or irregular over time and space and, each kind of dynamical behavior may be related to both normal and path...

Self-sustaining oscillations are essential for diverse physiological functions such as the cell cycle, insulin secretion and circadian rhythms. Synthetic oscillators using biochemical feedback circuits have been generated in cell culture. These synthetic systems provide important insight into design principles for biological oscillators, but have limited similarity to physiological pathways. He...

Circadian clocks drive biological rhythms with a period of approximately 24 hours and keep in time with the outside world through daily resetting by environmental cues. While this external entrainment has been extensively investigated in the suprachiasmatic nuclei (SCN), the role of internal systemic rhythms, including daily fluctuations in core temperature or circulating hormones remains debat...