Background: Psoriasis is a chronic-relapsing inflammatory skin disorder, in whose pathogenesis oxidative stress is suggested to be involved. Among different enzymes that play a role in maintaining the cellular redox balance, we aimed to assess the alteration of glutathione peroxidase (GPX) activity in cutaneous lesions and its correlation with the disease severity, firstly, to support the possi...

Background: Behcet’s disease is a recurrent, chronic and multi-systemic disease, which is determined by mucocutaneous manifestations. It spreads all over the world. The most common areas are in the Middle East, Mediterranean and Far East. Objective: The aim of this study was to determine the frequency of clinical manifestations of Behcet’s disease in patients admitted to dermatology ward ...

Radiation-induced skin injury ranges from acute dermatitis to chronic skin changes. Acute skin injury occurs during the course of radiation treatment and may take 1 to 3 months after the completion of radiation therapy to completely heal. Patients with mild acute dermatitis present with mild erythema, dry desquamation, pruritus, hyperpigmentation, and hair loss. Severe acute dermatitis is chara...

Atopic Eczema (AE) is a very common chronic skin inflammatory disease characterized by flares and remission phases [1]. AE is the most common form of inflammatory skin diseases affecting up to 20% of children [2]. It is a typical disease of paediatric age with 90% of cases appearing before 5 years of age. However it could persist in adult age in 30% of affected patients [3]. Recently Margolis e...

Background: Lichen planus (LP) is a chronic inflammatory disease involving the skin, mucous membranes and appendages. Like other chronic inflammatory diseases, it may be associated with metabolic disorders and dyslipidemia. Due to the discrepancies in the results of previous studies and lack of a similar study on an Iranian population, we decided to investigate and compare the serum lipid...

Background: Pruritic skin disorders are one of the most common disorders in elderly. Objective: To find out the prevalence of pruritic skin disorders in the elderly residing in Kahrizak Institute in Tehran. Patients and Methods: In this descriptive, cross sectional survey, all the elderly over 60 years of age without dementia residing in Kahrizak Institute in Tehran in the first 6 months ...

Background: Psoriasis vulgaris is a common chronic and inflammatory disease of skin that its etiology is not completely known. However, it seems that genetic and environmental factors play a role in this disease. In vitro studies show that prolactin as a neurohormone has an etiologic effect on psoriasis. This study aimed to compare serum prolactin levels in psoriatic patients with control group...

Psoriasis is a chronic skin disease that affects millions of people worldwide. Its etiology not yet fully understood, but it thought to be related combination genetic, immunological and environmental factors. In this literature review article, several relevant scientific studies publications will analyzed provide an overview psoriasis treatment. Aspects such as epidemiology, the significance di...