Background: Glucocorticoids (GC), bisphosphonates (BP), non-steroidal anti-inflammatory drugs (NSAID) and classical synthetic or biological disease-modifying antirheumatic (cs/bDMARD) have been employed in the treatment of chronic recurrent multifocal osteomyelitis (CRMO) non-bacterial (CNO). 1, 2 This one is a rare bone childhood illness none guidelines carried out till present. 3 Objectives: ...