We studied the relationship between gastroduodenal inflammation and the presence of Campylobaeter pylori from biopsy specimens of the gastric mucosa in 91 patients with gastritis with or without ulcers and 9 controls, healthy or suffering from other diseases. 68 of the patients were positive for the presence of C. pylori in their gastric mucosa. C. pylori was confirmed bacteriohistological...

Chronic gastritis and gastric atrophy are common in later adult life. Hebbel (1943) investigated the incidence of chronic gastritis at necropsy in patients dying from a variety of causes but whose history revealed no evidence of gastric symptoms. He found that gastric changes of any degree were rare below the age of 30 years and severe changes uncommon below the age of 50 years. Atrophic gastri...

background and objective: long period risk of gastric carcinoma in people affected with chronic helicobacter pylori gastritis is 5 times more than normal people. perhaps histological changes due to helicobacter pylori infection could be used for screening people at risk of gastric carcinoma and peptic ulcer. materials and methods: this study has been carried out as a cross-sectional process and...

A large amount of epidemiological evidence has accumulated indicating a significant relationship between Helicobacter pylori (Hp) infection and chronic gastritis [1,2], peptic ulcers [3], intestinal metaplasia [4,5], and adenocarcinoma [6–8] or lymphoma [9] development. In 1994, the World Health Organization/International Agency for Research on Cancer concluded that “Hp is a definite carcinogen...

Helicobacter pylori is one of the most common causes of chronic gastritis. With the development of the disease cellular inflammatory infiltrates composed of lymphocytes, plasma cells, and macrophages are formed in epithelium and lamina propria of the stomach. These cells are capable of secreting a number of active substances, including inducible nitric oxide synthase (iNOS). We examined the rel...

One hundred patients who had undergone operation for duodenal ulcer (68 vagotomy and gastroenterostomy; seven vagotomy and pyloroplasty; 22 gastrectomy and three gastroenterostomy) 10 or more years previously each underwent endoscopy. Biopsies were taken and gastric juice aspirated for measurement of pH and nitrite concentration. Patients were divided into five histological grades; chronic supe...

Histological samples of organs obtained from 72 (35 male and 37 female) cynomolgus monkeys (M. fascicularis) negative control groups in 12 toxicological studies were analyzed retrospectively. The most common processes where focal accumulations exogenous pigment found 76.4% animals the lungs, non-atrophic chronic gastritis, which was observed 37.4% animals, quiescent colitis noted 36.1% cases, i...

Fourteen patients were selected with advanced superficial chronic gastritis (grade II), marked chronic gastritis with partial atrophy (grade III), or chronic gastritis with total atrophy in which intestinal metaplasia was observed (grade IV). Azathioprine was administrated to all of them for periods varying from two and a half to six months. There were no side effects except in one patient, in ...