Macroscopically, renal oncocytomas are solitary, wellcircumscribed, slightly lobulated solid tumors with generally mahogany brown or dark red cut surface. A central scar is frequently observed. Necrosis and hemorrhage are uncommon. Microscopically, tumor cells with abundant, granular cytoplasm are arranged in nests, tubulocystic, solid, or trabecular patterns within edematous, myxomatous or hya...

The presence of myofibroblasts has been elucidated in neoplastic capsules of various organs. In the present article, we examine the presence of myofibroblasts in the capsule of renal cell carcinoma (RCC) and discuss the origin of the myofibroblasts. Nineteen renal tumors (conventional RCC, n=17; chromophobe RCC, n=2) with evident and totally surrounded fibrous capsule were selected. Abundant my...

New fluorescent Fluolid dyes have advantages over others such as stability against heat, dryness, and excess light. Here, we performed simultaneous immunostaining of renal tumors, clear cell renal cell carcinoma (RCC), papillary RCC, chromophobe RCC, acquired cystic disease-associated RCC (ACD-RCC), and renal angiomyolipoma (AML), with primary antibodies against Kank1, cytokeratin 7 (CK7), and ...

Introduction Notch signalling, an evolutionarily conserved mechanism of cellular differentiation and tissue remodelling, is frequently deregulated in several human malignancies, including renal cell carcinoma (RCC). However, the prognostic value of individual Notch pathway members in RC subtypes remains indefinable. The present study investigates whether the differential expression of Notch mem...

A 60-year-old Japanese male with a chromophobe cell carcinoma of his left kidney is reported. The tumor, 18 x 27 mm in size, was incidentally found by abdominal ultrasonography. Computed tomography and magnetic resonance imaging demonstrated a well-demarcated solid tumor arising from the lower pole of the left kidney. Histopathological examination of the surgically removed tumor revealed that i...

Background: Bilateral renal cell carcinoma (RCC) is an extremely rare renal tumor, even more infrequently with two different types of pathology. Methods: We present a case of bilateral RCC with simultaneous retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) in a 56-year-old male patient. Results: The postoperative histopathologic examination indicated that the left was clear cell carc...

Background: Bilateral renal cell carcinoma (RCC) is an extremely rare renal tumor, even more infrequently with two different types of pathology. Methods: We present a case of bilateral RCC with simultaneous retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) in a 56-year-old male patient. Results: The postoperative histopathologic examination indicated that the left was clear cell carc...

Objective: Bilateral renal cell carcinoma (RCC) is an extremely rare renal tumor, even more infrequently with two different types of pathology. Methods: We present a case of bilateral RCC with simultaneous retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) in a 56-year-old male patient. Results: The postoperative histopathologic examination indicated that the left was clear cell carci...