PURPOSE To update the findings from the Choroidal Neovascularization Prevention Trial (CNVPT) with respect to resolution of drusen, incidence of choroidal neovascularization, and visual function. DESIGN A multicenter, randomized, controlled, pilot clinical trial. PARTICIPANTS The 120 patients enrolled in the CNVPT. Patients had signs of choroidal neovascularization or retinal pigment epithe...

In ophthalmology, as in medicine generally, there has been a rapid development of treatment to combat infections and allergic conditions, but the choice of therapy for degenerative, hereditary conditions is-admittedly-just as small as before. The proportionate role played by the genetic degenerative eye lesions as causative factors of blindness, or impaired vision, has thus greatly increased. R...

purpose: to report a young patient with microphthalmos associated with bilateral papillomacular fold and severe hyperopia case report: in this observational case report, a sixteen-year-old young man was referred with high hyperopia to al-zahra eye hospital, zahedan university of medicalf sciences, zahedan, iran, for check up. spherical error in right eye (re) was +14.75 d and in the left eye (l...

Papadopoulou et al are to be congratulated for submitting an informative article regarding the management of small choroidal melanoma with pertinent discussion and various educational points to remember. We were, however, surprised, not to find the use of OCT (optical coherence tomography) as part of the management to help the diagnosis or in the discussion section. The authors correctly highli...

PURPOSE To study the changes in the choroidal layers thickness with age in a healthy population using swept-source optical coherence tomography. METHODS Retrospective data analysis of a subgroup of eyes from a previous single-center, prospective, cross-sectional, noninterventional study. One hundred and sixty-nine healthy eyes were evaluated using swept-source optical coherence tomography. In...

PURPOSE To evaluate changes in axial length and choroidal thickness after trabeculectomy. PATIENTS AND METHODS Fourteen patients under 80 years of age with glaucoma, were enrolled. The choroid was imaged using prototypical high-penetration optic coherence tomography (OCT) and the thickness was measured. Axial length, choroidal thickness, and intraocular pressure (IOP) were measured bilaterall...

AIMS/BACKGROUND A prolonged choroidal filling phase on fluorescein angiography has been reported to be a common finding and associated with visual function abnormalities in patients with age-related macular degeneration (AMD). This investigation was carried out to determine whether this perfusion defect was related to the slowing of foveal cone electroretinogram (ERG) implicit time seen in pati...

Purpose. To investigate the correlation between aqueous and serum levels of pigment epithelium-derived factor (PEDF) and macular choroidal thickness in high myopia patients, both with and without choroidal neovascularization (CNV). Methods. Serum and aqueous levels of PEDF were measured by enzyme-linked immunosorbent assay in 36 high myopia patients (36 eyes) with no CNV (non-CNV group), 14 hig...

BACKGROUND The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative external-beam radiotherapy for large choroidal melanomas. The third arm is an ...

Choroidal effusions may appear as subtle abnormalities on CT scans. Recognition of choroidal effusions, however, is critical because they may be an early sign of ocular pathologic abnormality. After detection, the various causes of choroidal effusions, such as carotid cavernous fistulas, ocular hypotony, tumors, and inflammatory conditions, should be considered.