نتایج جستجو برای: cholesterol ester transfer protein

تعداد نتایج: 1585710  

2016
Anna Skoczyńska Anna Wojakowska Barbara Turczyn Katarzyna Zatońska Maria Wołyniec Natalia Rogala Andrzej Szuba Grażyna Bednarek-Tupikowska

BACKGROUND Plasma cholesteryl ester transfer protein (CETP) activity is often decreased in patients with hypothyroidism, whereas less is known about the phospholipid transfer protein (PLTP). We aimed to evaluate simultaneously serum CETP and PLTP activity in patients diagnosed with hypothyroidism. MATERIAL AND METHODS The selection criteria for control group members (without thyroid dysfunction...

Journal: :Journal of lipid research 1989
P E Fielding E M Jackson C J Fielding

The response of parameters of plasma cholesterol metabolism was studied in baboons adapted either to a low-fat, low-cholesterol diet or a high-fat, high-cholesterol diet. Animals adapted to the low-fat diet responded to a single low-fat or high-fat meal, as do normal humans, by a stimulation of cholesterol transport from blood cells to plasma, a stimulation of esterification of cholesterol, and...

Journal: :Arteriosclerosis 1984
J J Albers J H Tollefson C H Chen A Steinmetz

A highly purified protein that facilitates the exchange and net mass transfer of cholesteryl ester (CE), and triacylglycerol (TG), and the transfer of phosphatidylcholine (PC), between plasma lipoproteins was isolated from the d-1.21-1.25 g/ml plasma fraction. Transfer activities showed similar distributions through ultracentrifugation, phenyl-Sepharose, DEAE-Sepharose, CM-cellulose, and hydrox...

Journal: :Arteriosclerosis 1988
S Stender E Hjelms

For the study of cholesteryl ester transfer from different plasma lipoproteins into human aortic tissue, patients scheduled for reconstructive aortic surgery were intravenously injected with autologous in vitro labeled lipoproteins 20 to 24 hours before aortic intima-media samples were obtained during the operation. The injectate contained high density lipoproteins (d greater than 1.063) labele...

Journal: :The Journal of clinical investigation 2006
Fumihiko Matsuura Nan Wang Wengen Chen Xian-Cheng Jiang Alan R Tall

Genetic deficiency or inhibition of cholesteryl ester transfer protein (CETP) leads to a marked increase in plasma levels of large HDL-2 particles. However, there is concern that such particles may be dysfunctional in terms of their ability to promote cholesterol efflux from macrophages. Recently, the ATP-binding cassette transporter ABCG1, a macrophage liver X receptor (LXR) target, has been s...

Journal: :The Journal of biological chemistry 1991
X C Jiang P Moulin E Quinet I J Goldberg L K Yacoub L B Agellon D Compton R Schnitzer-Polokoff A R Tall

The plasma cholesteryl ester transfer protein (CETP) catalyzes the transfer of cholesteryl esters from high density lipoproteins (HDL) to triglyceride-rich lipoproteins and plays a major role in the catabolism of HDL. Lipoprotein lipase (LPL) is the rate-limiting enzyme for hydrolysis of circulating triglyceride and is involved in HDL formation. We show that tissues containing LPL are major sou...

Journal: :Internal medicine 2007
Shin-ichiro Miura Keijiro Saku

A low high-density lipoprotein cholesterol (HDL-C) level is one of the strongest predictors of coronary risk (1). The negative correlation between coronary artery disease (CAD) and plasma HDL-C has been attributed to the ability of HDL to take up cellular cholesterol from the periphery and to mediate the transport of excess cholesterol to the liver (reverse cholesterol transport, RCT) (2). In J...

2016
Yunqin Chen Jibin Dong Xueying Chen Hui Jiang Ahmed Bakillah Xiaojin Zhang Zhiqiang Li Jia Yin Donghui Liang Yunzeng Zou Mahmood Hussain Marina Cuchel Daniel Rader Haozhu Chen Junbo Ge Xian-Cheng Jiang

BACKGROUND Serum preβ1-high density lipoprotein (preβ1-HDL) was defined by two-dimensional non-denaturing linear gel electrophoresis and apolipoprotein A-I immuno-blotting. Serum preβ1-HDL seems to play an important role in reverse cholesterol transport, a well-known anti-atherosclerosis process. However, there are still debatable questions for its quantification and coronary artery disease (CA...

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