PURPOSE Facial paralysis is an uncommon but significant complication of chronic otitis media (COM). Surgical eradication of the disease is the most viable way to overcome facial paralysis therefrom. In an effort to guide treatment of this rare complication, we analyzed the prognosis of facial function after surgical treatment. MATERIALS AND METHODS A total of 3435 patients with COM, who under...

Abstract Background Cholesteatoma is an atticoantral disease that potentially causes life-threatening complications. Therefore, canal wall down mastoidectomy a well-established technique to eradicate the disease, especially in extensive cholesteatoma. Aim To evaluate status of dry ear and hearing outcome post-retrograde mastoidectomy. Methods A retrospective study patients with cholesteatoma wh...

Background: During last decades, many otologists attempted to make a long standing dry ear, resulting in better hearing after cholesteatoma surgery. This study evaluated the prognosis of two common methods of cholesteatoma ear surgery considering ten years follow-up. Methods: This retrospective analysis was done using medical records of 108 adult patients with cholesteatoma. After ten years of ...

Complications of middle ear cholesteatoma are well described in the literature and are classified into two major categories: intratemporal and intracranial. They are due either to infection or to local extension of the disease and consequent invasion of surrounding tissues. We describe an unusual case of an extratemporal complication in a young woman who was treated at our service. Ten years pr...

This study presents a preliminary trial for a new classification of cholesteatoma that allow comparison of cases and standardization of management. All previous attempts failed to gain acceptance because of the lack of clinical relevance. Objective: Trial of a new simple practical system to stage cholesteatoma based only on the extent of the lesion, utilizing microscopic and endoscopic examinat...

OBJECTIVES To investigate the expression of prostaglandin E2 receptor subtypes, E-prostanoid (EP) 1-4 receptors, in acquired cholesteatoma and its possible role in the pathologic process of this disorder. METHODS Specimens of human acquired cholesteatoma were obtained from 29 patients and 19 skin biopsies of normal external auditory canal were as controls. The mRNA and protein expression of E...

UNLABELLED Conventional CT and MRI scans have low specificity when it comes to differentiating granulation tissue from relapsing cholesteatoma. AIM this paper aims to analyze the use of DWI and delayed post-contrast T1-weighed imaging in the detection of recurring cholesteatomas. MATERIALS AND METHOD this is a cross-sectional prospective study that looked at 17 cholesteatoma patients postop...

OBJECTIVE To describe the clinical manifestations of external auditory canal (EAC) cholesteatoma and evaluate the surgical outcomes of reconstruction using an inferior pedicled soft-tissue periosteum flap. MATERIALS AND METHODS A total of 28 patients were enrolled in this retrospective study conducted at Kaohsiung Medical University Hospital in Taiwan between January 2004 and December 2013. E...

Cholesteatomas are benign epidermally‑derived lesions of the temporal bone that are caused by migration of hyperproliferative keratinocytes into the middle ear and mastoid cavity. The molecular mechanisms that regulate the pathogenesis of cholesteatomas are currently not fully understood. The present study demonstrated the antigrowth and anti‑invasive effects of let‑7a microRNA (miRNA) on chole...