To investigate the possible long-term consequences of gestational exposure to cannabinoids on cognitive functions, pregnant rats were administered with the CB1 receptor agonist WIN 55,212-2 (WIN), at a dose (0.5 mgkg) that causes neither malformations nor overt signs of toxicity. Prenatal WIN exposure induced a disruption of memory retention in 40- and 80-day-old offspring subjected to a passiv...

A study was conducted in the alluvial soils located in Oko-anala in Delta State, Nigeria. These alluvial soils are primarily used for intensive vegetable production for commercial purposes. The total land area of about 3.34 Square kilometer was divided into three consociations and composite soil samples collected from pre-determined depths of 0-15 and 16-30cm. The samples were routinely prepare...

Experiments using electrical stimulation of different groups of muscle afferent nerve fibres have shown that most of the known medullated fibres in muscle nerves are involved in reflexly stimulatihg ventilation (Bessou et al. 1959, Koizumi et al. 1961, Senapati 1966). Investigations using natural stimulation of muscle receptors and pmsive limb movements (Kao et al. 1963, Senapati 1966, Kalia et...

BACKGROUND A growing body of evidence suggests that some cardiovascular drugs could modulate the level of proinflammatory cytokines. Therefore, the aim of the present study was to investigate whether celiprolol, a third generation β-adrenoceptor blocker, affects lipopolysaccharide (LPS)-induced serum concentrations of TNF-α, IL-1β, IL-6 in normotensive (WKY) and spontaneously hypertensive (SHR)...

An acute acoustic trauma (AAT) results when the unprotected ear is exposed to very high sound pressure levels, usually as the result of an industrial or milita~ accident. A study was performed to evaluate the effects of a corticosteroid (dexamethasone) on the hearing loss from a series of blast waves that would simulate an AAT. Groups of chinchillas were exposed individually to ten 160-dB peak ...

ascorbic acid (vitamin c) supplementation has been documented as a useful tool to improve the performance of laying birds reared under harsh environmental conditions. however, there is limited information on the use of ascorbic acid as a means of ameliorating the stressful conditions imposed by feed restriction. to this effect a 3 × 2 factorial experiment was carried out to evaluate the effect ...

BACKGROUND This study was conducted to elucidate if nitric oxide is released by the porcine jejunal mucosa upon selective stimulation of AT2 receptors and the possible involvement of iNOS, and to investigate the presence of jejunal AT1 and AT2 receptors. Young landrace pigs were anaesthetized with ketamine and alpha-chloralose. Jejunal luminal NO output was assessed by intraluminal tonometry an...

In this paper, the contamination level of fourteen elements (Al, Ca, Mg, V, Ti, Na, Mn, As, Br, La, Sm, Sc, U, Yb) from different soil samples of the nuclear reactor surrounding areas in Savar, Bangladesh was investigated with instrumental neutron activation analysis (INAA) method. Generally, neutron activation is most reliable tool for determining the concentration of the trace elements and he...

Increased environmental pollution has necessitated the need for eco-friendly clean-up strategies. Filamentous fungal species from gold and gemstone mine site soils were isolated, identified and assessed for their tolerance to varied heavy metal concentrations of cadmium (Cd), copper (Cu), lead (Pb), arsenic (As) and iron (Fe). The identities of the fungal strains were determined based on the in...