Previously, we showed that chitin synthase 2 (Chs2) is required for septum formation in Saccharomyces cerevisiae, whereas chitin synthase 1 (Chsl) does not appear to be an essential enzyme. However, in strains carrying a disrupted CHS1 gene, frequent lysis of buds is observed. Lysis occurs after nuclear separation and appearg to result from damage to the cell wall, as indicated by osmotic stabi...

In a previous paperX), we reported a new chitinase inhibitor, cyclo(L-Arg-D-Pro) from marine bacteria. At the budding cell stage of Saccharomyces cerevisiae, chitin is known to be a main constituent of the primary septum between the mother and daughter cells2). Amongthe chitin metabolite enzymes, chitin synthase is essential for the septum formation3). It is known that polyoxin D inhibits chiti...

Presently, the snail shells produced wastes that are detrimental to clean immediate environment while over reliance on synthesized polymer suicidal because they not degradable. Hence, biological production of through recycling will signal an ending consequences associated with and synthesis. Therefore, current study is targeted at chitosan extraction, characterization from snail.  Shells w...

Previously, we showed that chitin synthase 2 (Chs2) is required for septum formation in Saccharomyces cerevisiae, whereas chitin synthase 1 (Chsl) does not appear to be an essential enzyme. However, in strains carrying a disrupted CHS1 gene, frequent lysis of buds is observed. Lysis occurs after nuclear separation and appearg to result from damage to the cell wall, as indicated by osmotic stabi...

Chitin hydrolases have been identified in a variety of organisms ranging from bacteria to eukaryotes. They have been proposed to be possible targets for the design of novel chemotherapeutics against human pathogens such as fungi and protozoan parasites as mammals were not thought to possess chitin-processing enzymes. Recently, a human chitotriosidase was described as a marker for Gaucher diseas...

One of the essential features of fungal morphogenesis is the polarized synthesis of cell wall components such as chitin. The actin cytoskeleton provides the structural basis for cell polarity in Aspergillus nidulans, as well as in most other eukaryotes. A class V chitin synthase, CsmA, which contains a myosin motor-like domain (MMD), is conserved among most filamentous fungi. The DeltacsmA null...