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Background Pulmonary thromboembolism (TEP) is related to the migration of thrombotic material from the systemic venous circulation to pulmonary vascular tree, with obstruction of the pulmonary arterial circulation. The mortality rate is 30% in non-identifiable forms, and 2-8% in those treated earlier. The early use of thrombolytics determines the success of the lysis. Thrombolysis is considered...

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Abstract Treatment of 11,12‐bis(1,1’‐biphenyl‐3‐yl or 6‐phenylpyridin‐2‐yl)‐substituted 11,12‐dihydro‐indolo[2,3‐ a ]carbazole with an oxidizing system Pd(II)/Ag(I) induced effective double dehydrogenative cyclization to afford the corresponding π‐extended azahelicenes. The optical resolutions were readily achieved by preparative chiral HPLC. It was found that pyridopyrrolo‐carbazole‐based azah...