Brett, E. M., Ellis, R. B., Haas, L., Ikonne, J. U., Lake, B. D., Patrick, A. D., and Stephens, R. (1973). Archives of Disease in Childhood, 48, 775. Late onset GM2-gangliosidosis: clinical, pathological, and biochemical studies on 8 patients. Eight cases of late onset Gm,-gangliosidosis are described. 4 presented before the age of 2 years and 4 between 3j and 10 years. Gait disturbance, intell...

Sandhoff disease is a GM2 gangliosidosis that is rare in Thailand. The authors report a Thai family with two children known to have infantile form of Sandhoff disease. The index case exhibited mitral valve prolapse with mitral regurgitation as an early sign, which is a rare presentation in Sandhoff disease. Thereafter the patient had developmental regression, startle reaction, and cherry red sp...

Waren Tay was born in 1843; he qualified in medicine at the London Hospital and was appointed to it as a surgeon. He was also on the staff of the Royal London Ophthalmic Hospital at Moorfields and City Road, and the North East Hospital for Children, which became Queen Elizabeth Hospital, Hackney Road. A versatile man, he was also dermatologist to the Hospital for Diseases of the Skin. In 1881 h...

Severe vaso-occlusive retinopathy as the initial manifestation of systemic lupus erythematosus (SLE) is rare. We report a 16-year-old female who developed bilateral visual impairment. Fundus examinations showed bilateral "cherry-red spot" appearance, multiple confluent cotton wool spots, and widespread arterial occlusion. Laboratory studies showed leukopenia, antinuclear antibody (+), and anti-...

A 27-year-old female presented with sudden visual loss of her right eye after receiving an autologous fat injection into the right nasolabial fold. Fundus examination of the right eye showed multiple whitish patchy lesions with macular edema. Fluorescein angiogram showed deterioration of choroidal circulation with patchy choroidal filling and arm-to-retina circulation time and retinal arteriove...

BACKGROUND Blindness after spinal surgery is a rare complication, but it is serious, irreversible and incurable. Central retinal artery occlusion (CRAO) is rare after spinal surgery and ophthalmoplegia is even rarer. CASE A 52-year-old male patient complained of loss of vision in right eye immediately after cervical spine surgery. On examination, the patient's visual acuity in right eye was a...

BACKGROUND Central retinal artery occlusion (CRAO) is an arterial ischemic stroke, rarely occurred in children accompanied with asymptomatic cerebral infarction and almost never involved in severe pneumonia related to Mycoplasma pneumonia infection. CASE PRESENTATION An 8-year-old boy with severe pneumonia related to Mycoplasma pneumonia infection that developed loss of vision in the left eye...

Ocular involvement in Churg-Strauss syndrome is infrequent. We describe the case of a 54-year-old woman with eosinophilia and involvement of the respiratory tract, skin, and peripheral nervous system, fulfilling the American College of Rheumatology criteria for Churg-Strauss syndrome. The patient presented with acute, painless vision loss in her right eye. Central retinal artery occlusion (CRAO...

In this article, we describe the development of an autonomous robot, Cherry the Little Red Robot, whose functionality we designed so that she could socially interact with humans on a daily basis in the context of an office suite environment. Cherry has a given set of office-tasks to accomplish, from giving tours of our computer science faculty suite to visitors, to serving beverages to those fa...