conclusions the result of the current study showed the growing number of nosocomial infections associated with xdr a. baumannii causing difficulties in antibiotic therapy. resistant strains increasingly cause public health problems; therefore, their early detection is essential for healthcare centers. results among the 121 isolated a. baumannii, 44% and 56% were isolated from female and male, r...

One of the most common pathogens in infection of hydrogel contact lens wearers is Pseudomonas aeruginosa, which can gain access to the eye via contamination of the lens, lens case, and lens care solutions. Only one strain per species is used in current regulatory testing for the marketing of chemical contact lens disinfectants. The aim of this study was to determine whether P. aeruginosa strain...

In a paper recently published in this Journal (1) we reported the isolation of the phenolic acid commonly known as protocatechuic acid (3,4-dihydroxybenzoic acid) from the outer bulb scales of pigmented onions. The occurrence of this acid in the outer scales has a significant relationship to disease resistance in the onion. Protocatechuic acid is apparently one of the chemical entities that ena...

Multidrug resistance is a condition enabling disease causing microorganism to resist distinct drugs or chemical of wide variety structure and function targeted at eradicating the bacteria. Microorganisms that display multidrug resistant can be pathogenic cells. In this study, table eggs are used commonly, because it considered most nutritious economical source protein part healthy diet. However...

Validation of Chemical and Non-Chemical Antimicrobial Interventions Applied Preand Post-Chilling to Reduce Microbial Populations in Broiler Carcasses. (August 2007) Veronica Alejandra Molina, B.Sc., Zamorano Panamerican Agricultural University Chair of Advisory Committee: Dr. Marcos X. Sánchez-Plata Higher risks of food-borne illness associated with increased consumption of poultry products mak...

introduction candidiasis as an opportunistic infection is created by some species of candida. here the role of candida albicans is more noticeable than other species. candida can cause an extended spectrum of symptoms. due to the increasing consumption of immunosuppressants including corticosteroids and diseases like diabetes, candidiasis has drawn more attention than before. methods considerin...

background metallo-beta-lactamase (mbl) producing pseudomonas aeruginosa in the burn patients is a leading cause of morbidity and mortality and remains a serious health concern among the clinicians. objectives the aim of this study was to detect mbl-producing p. aeruginosa in burn patients and determine multidrug-resistant (mdr) strains, and respective resistance patterns. patients and methods ...

thioguanine is attributable to incorporation of the anti metabolite into deoxyribonucleic acid (DNA) and that re sistance may be the result of a lower capacity for such in corporation; and (d) Paterson (17, 19), using a 6-mercap topurine-resistant Ehrlich carcinoma, proposed a decreased rate of transport of drug across the cell membrane as a possible mechanism for the resistant character of thi...

There is an increasing flow of new antituberculosis chemical entities entering the tuberculosis drug development pipeline. Although this is encouraging, the current number of compounds is too low to meet the demanding criteria required for registration, shorten treatment duration, treat drug-resistant infection, and address pediatric tuberculosis cases. More new chemical entities are needed urg...

One of the most significant hurdles to developing new chemical probes of biological systems and new drugs to treat disease is that of understanding the mechanism of action of small molecules discovered with cell-based small-molecule screening. Here we have assembled an ordered, high-expression clone set of all of the essential genes from Escherichia coli and used it to systematically screen for...