Daniel T. Kaplan,1,2 John R. Clay,3,4 Timothy Manning,1 Leon Glass,1,2 Michael R. Guevara,1,2 and Alvin Shrier2,4 1Centre for Nonlinear Dynamics, McGill University, Montreal, Quebec, Canada H3G 1Y6 2Physiology Department, McGill University, Montreal, Quebec, Canada H3G 1Y6 3Laboratory of Neurophysiology, National Institutes of Health, Bethesda, Maryland 20892 4Marine Biological Laboratory, Wood...

BACKGROUND In Togo, about half of health care costs are paid at the point of service, which reduces access to health care and exposes households to catastrophic health expenditure (CHE). To address this situation, the Togolese government introduced a National Health Insurance Scheme (NHIS) in 2011. This insurance currently covers only employees and retirees of the State as well as their depende...

2014 Chronic hand eczema (CHE), an inflammatory skin disease, places heavy psychosocial and economic burden on the affected individual and society as a whole. Patch testing is recommended to identify potential causative allergens in each patient. Efficacy of traditional topical treatments render the management of CHE challenging. Oral alitretinoin (9-cis-retinoic acid) is a new drug for the tre...

Cholinesterases (ChE) acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are capable for hydrolyzing esters. Our previous structure-activity analysis of ChE substrates showed that extended conformation of substrate choline moiety is productive for hydrolysis by AChE and its semi-folded conformation is productive for hydrolysis by BChE. The formation of activated complex between ChE an...

Objective- This study examined the effect of Crataegus hydroalcoholic extract (CHE) on intestinal ischemia-reperfusion (I/R) in rats. Design- Experimental study Animals- 25 adult male Wistar rats Procedures- Rats weighing 200±25 g were randomly divided into five individual groups as follows: sham group without...

In the present study fungi collections were sampled in the Sangay (SP) and Llanganates (LP) National Parks, from which sequences of the regions of the internal transcribable spacer (ITS1-5.8S-ITS2) of the ribosomal DNA were obtained (RDNA). The taxonomic identification of fungi of the order Xylariales was achieved with the bioinformatic tools, to further study the phylogenetic relationships amo...

Generally nonchemotactic mutants of Escherichia coli and Salmonella typhimurium were analyzed by interspecies complementation tests to determine the functional correspondence between the che genes of these two organisms. The E. coli che region was introduced into Salmonella recipients by means of a series of F-prime elements. Wild-type che genes of E. coli F'420 complemented all che mutants of ...

Small molecule cholinesterase (ChE) inhibitors represent one of themost effective therapeutic strategies for the treatment of Alzheimer's disease (AD). However, only three of these drugs have entered the market. Understanding of the structures of successful ChE inhibitors is still very limited; therefore, it is an urgent task to identify new scaffolds for the design of ChE inhibitors. In the pr...

Sunto. – In questo lavoro si generalizzano alcuni risultati di [3] riguardanti la proprieta’ di alcune curve nodali, su superficie non-singolari in Pr, di essere ”geometricamente linearmente normali” (concetto che estende la ben nota proprieta’ di essere linearmente normale). Precisamente, per una data curva C, irriducibile e dotata di soli punti nodali come uniche singolarita’, che giace su un...

    Background: One of the main goals of health systems is to protect people against financial risks associated with diseases that can be catastrophic for patients. In 2014, Health Sector Evolution Plan (HSEP) was implemented in Iran; one of the objectives of HSEP was to reduce out-of-pocket payments and provide more financial protection for people. Therefore, the present study a...