نتایج جستجو برای: cfp 10 protein

تعداد نتایج: 2127958  

2017
Tatiana Pereira da Silva Carmem Beatriz Wagner Giacoia-Gripp Carolina A. Schmaltz Flavia Marinho Sant’Anna Maria Helena Saad Juliana Arruda de Matos Julio Castro Alves de Lima e Silva Valeria Cavalcanti Rolla Mariza Gonçalves Morgado

BACKGROUND Little is known regarding the restoration of the specific immune response after combined antiretroviral therapy (cART) and anti-tuberculosis (TB) therapy introduction among TB-HIV patients. In this study, we examined the immune response of TB-HIV patients to Mycobacterium tuberculosis (Mtb) antigens to evaluate the response dynamics to different antigens over time. Moreover, we also ...

Introduction: Tuberculosis (TB) has been considered as a main health problems of the present century. Unfortunately, it has been reported different protective responses against BCG vaccine, as only available vaccine against TB .The search for a new and improved vaccine against tuberculosis is currently a very active field of research. In this study, we have evaluated the relative effects of int...

Journal: :Journal of cell science 2013
Xiaojun Huang Ying Liu Ruiwu Wang Xiaowei Zhong Yingjie Liu Andrea Koop S R Wayne Chen Terence Wagenknecht Zheng Liu

Calmodulin (CaM), a 16 kDa ubiquitous calcium-sensing protein, is known to bind tightly to the calcium release channel/ryanodine receptor (RyR), and modulate RyR function. CaM binding studies using RyR fragments or synthetic peptides have revealed the presence of multiple, potential CaM-binding regions in the primary sequence of RyR. In the present study, we inserted GFP into two of these propo...

Journal: :Applied and environmental microbiology 2009
Inka Sastalla Kannie Chim Gordon Y C Cheung Andrei P Pomerantsev Stephen H Leppla

Fluorescent proteins have wide applications in biology. However, not all of these proteins are properly expressed in bacteria, especially if the codon usage and genomic GC content of the host organism are not ideal for high expression. In this study, we analyzed the DNA sequences of multiple fluorescent protein genes with respect to codons and GC content and compared them to a low-GC gram-posit...

Journal: :Journal of clinical microbiology 2004
Inger Brock Karin Weldingh Eliane M S Leyten Sandra M Arend Pernille Ravn Peter Andersen

The currently used method for immunological detection of tuberculosis infection, the tuberculin skin test, has low specificity. Antigens specific for Mycobacterium tuberculosis to replace purified protein derivative are therefore urgently needed. We have performed a rigorous assessment of the diagnostic potential of four recently identified antigens (Rv2653, Rv2654, Rv3873, and Rv3878) from gen...

2017
Hanhan Liu Chun Ding

The present study aimed to compare microbead injection with and without hydroxypropyl methylcellulose (HPM) in order to establish an experimental animal model of glaucoma. This model was established in C57BL/6 mice and transgenic mice expressing cyan fluorescent protein (CFP) under the control of the Thy1 promoter in retinal ganglion cells (RGCs). C57BL/6 mice aged between 12 and 20 weeks old w...

Journal: :IEEE Microwave Magazine 2021

Amir Teimourpour Mohsen Arzanlou Roghayeh Teimourpour Samira Rashidian Zahra Meshkat,

Background: Tuberculosis is a life threatening disease that is partially prevented by BCG vaccine. Development of more effective vaccines is an urgent priority in TB control. Ag85a and Tb10.4 are the members of culture filter protein (CFP) of M. tuberculosis that have high immunogenicity. Objective: To analyze the immunogenicity of Ag85a-Tb10.4 DNA vaccine by enzyme-linked immunosorbent as...

2014
Christian Poulsen Santosh Panjikar Simon J. Holton Matthias Wilmanns Young-Hwa Song

Members of the WXG100 protein superfamily form homo- or heterodimeric complexes. The most studied proteins among them are the secreted T-cell antigens CFP-10 (10 kDa culture filtrate protein, EsxB) and ESAT-6 (6 kDa early secreted antigen target, EsxA) from Mycobacterium tuberculosis. They are encoded on an operon within a gene cluster, named as ESX-1, that encodes for the Type VII secretion sy...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید