despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...

verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. it is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. it accounts for 1-2% of all laryngeal cancers. the clinical, histopathological and biologic fea...

perivascular epithelioid cell tumor (pecoma) is composed of hmb45+ epithelioid cells with clear to granular cytoplasm and perivascular distribution. we describe a uterine pecoma in a 33 years old woman where tumor cells were positive for hmb45 but negative for epithelial markers and negative or positive for smooth muscles markers.

background: we report the analgesic efficacy of lumbar epidural adenosine injection in reducing the chronic neuropathic pain in a patient with primitive neuroectodermal tumor. report of the case: in this case report a 13-year-old male with primary neuroectodermal tumor (pnet) was administered in epidural space with adenosine to reduce his pain. the patient received 10ml of 0.25% ropivacaine and...

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67gallium-bleomycin complex (67ga-blm) was prepared using thakour method. radio-thin-layer-chromatography of prepared complex showed a2 and b2 radiopeaks with rf at 0.7 and 0.4 respectively with a purity of above % 95. tissue uptake of 67ga-blm and 67gacl3 in twelve tissues including tumor, blood, liver, lung, spleen, muscle, skin, heart, kidney, colon, colon content ,bladder and the total body...

background and objective: germ cell tumor (gct) accounts for approximately 2-3% of all malignancies in children. in this respect, about 20% of patients with gct are still resistant to therapy. materials and methods: the cross-sectional strategy of this survey was undertaken on 57 patients with germ cell tumor who admitted to ali asghar children hospital during the years 1990- 2003. in this stud...

although the majority of mesenchymal lesions of the gastrointestinal tract are neoplastic in nature, but nonneoplastic reactive processes may also involve the gastrointestinal tract and mesentery. some more aggressive neoplasms located in same area, such as fibromatosis or gastrointestinal stromal  tumors  may  be  cause  of  diagnostic  confusion.  reactive  nodular  fibrous  pseudo  tumor (rn...

background and objectives: we aimed at evaluating the efficacy of fine needle aspiration biopsy (fna) in comparison with histopathology and demonstrating whether cytological study could be a proper diagnostic tool in orbital mass lesions. materials and methods: in a cross sectional study during 36 months, patients referred to our ophthalmologic center affiliated to tehran university of medical ...

salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  minor  salivary  gland  tumors (msgts) are uncommon and make up about 10% of all salivary gland neoplasms. the clinical and histopathological distribution of these tumors vary geographically. a case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. the tumor invaded into the anterior surf...