Background: Cervical cancer remains the leading cause of cancer death among women in developing country. In Iraqi Kurdistan Region, few women undergo screening and the incidence of cervical cancer is on the increase as is the case in most developing countries. The purpose of this study was to explore women’s individual factors affecting the performance of the cervical cancer screening in ...

The human mitochondrial ATP-dependent Lon protease functions in regulating the metabolism and quality control of proteins and mitochondrial DNA (mtDNA). However, the role of Lon in cancer is not well understood. Therefore, this study was undertaken to investigate the importance of Lon in cervical cancer cells from patients and in established cell lines. Microarray analysis from 30 cancer and 10...

Suppressor of cytokine signaling (SOCS) family is an important negative regulator of cytokine signaling and deregulation of SOCS has been involved in many types of cancer. All cervical cancer cell lines tested showed lower expression of SOCS1, SOCS3, and SOCS5 than normal tissue or cell lines. The immunohistochemistry result for SOCS proteins in human cervical tissue also confirmed that normal ...

Background: Epidemiological studies are shown robust association between human papillomavirus (HPV) and cervical cancer. From 1990 HPV was known as a necessary but insufficient cause of cervical invasive cancer. The purpose of this study was to evaluate the cost effectiveness of HPV test in cervical cancer screening. Materials and Methods: This is a systematic review article; the newest scienti...

BACKGROUND HPV DNA has been detected in metastatic tumour and HPV plasma viraemia may indicate a poor prognosis and a high risk for metastasis. OBJECTIVE Detection of HPV DNA in plasma of patients with cervical carcinoma. STUDY DESIGN A cross-sectional study was done, wherein cervical biopsies and plasma samples were collected from 58 women with invasive cervical carcinoma, 10 women with ce...

Cervical cancer is a disease characterized by the growth of abnormal cells in cervical tissue. mostly caused Human Papillomavirus (HPV) types 16 and 18. The role genetic factors development malignancy mediated presence mutation HPV oncogene, especially oncogenes E6 E7. Oncogenic proteins E7 initiate dysregulation cellular proliferation apoptotic mechanisms targeting tumor suppressor proteins, s...

Tisotumab vedotin-tftv (TIVDAK®), a tissue factor-directed antibody-drug conjugate, is valuable option for the treatment of adult patients with recurrent or metastatic cervical cancer experiencing disease progression on after chemotherapy in USA. In clinical trial previously treated cancer, tisotumab intravenous infusion led to clinically meaningful and durable antitumor activity. The tolerabil...

Objective: To carry out dosimetric comparison between volumetric modulated arc therapy (VMAT) and intensity-modulated radiation (IMRT) in cervical cancer. Methods: 50 postoperative cancer patients were included this study. The admitted for treatment from January 2021 to 2022. VMAT IMRT plans designed each patient analyze the dose distribution target area of two techniques. Results: Comparing mo...

Based on the accumulated data, FTIR spectroscopy seems to be a highly sensitive tool in cervical cancer diagnosis. We, therefore, employed this technique in a screening type of research here in Tehran. The purpose of this study was to look for the spectral pattern differences between normal and malignant cervix samples in Iranian women. Through formal and informal announcements, all gynecology ...

background : the aim of this study was to describe the coverage for cervical cancer screening among the visitors of a food exhibition in brussels, belgium and to describe the factors that affect their participation in the screening programs. methods : the participants aged between 25 and 64 years were recruited during a food exhibition at the brussels exhibition centre from 6 until 21 october 2...