Aim. To study brain magnetic resonance imaging (MRI) changes in patients with resistant hypertension (HTN) after renal denervation (RD) and its cerebral protection effectiveness. Material methods. The included 111 patients, of whom 50 were men (45%) 61 women (55%), who underwent RD. mean number antihypertensive drugs taken regularly was 4,1±1,1. All MRI 24-hour ambulatory blood pressure monitor...