The antibacterial activity of some antimicrobials may be under-estimated during in vitro microbiological susceptibility tests, due to their instability under such conditions. The in vitro degradation of seven widely used antimicrobials (amoxicillin, cephalexin monohydrate, cefotaxime sodium salt, ciprofloxacin, erythromycin hydrate, clarithromycin, and doxycycline hyclate) and its effect on MIC...

therapy in resistant enteric fever, various drugs singly, or in combination, such as cotrimoxazole and cephalosporins, or cephalexin and gentamicin, third generation cephalosporins and newer quinolones have been tried with varying results. This communication describes our observations on the clinical profile of children with enteric fever due to MDRST infection and, compare different drug regim...

We tested in vitro the activities of streptomycin and tetracycline--antibiotics that have long been used to treat rhinoscleroma--as well as several newer oral agents by using 23 isolates of the causative organism Klebsiella rhinoscleromatis. All isolates were inhibited by clinically achievable concentrations of trimethoprim-sulfamethoxazole, amoxicillin-clavulanate, chloramphenicol, ciprofloxac...

The efficacy of single-dose therapy with 3 g of cephalexin was evaluated in 129 women with symptoms of acute uncomplicated lower urinary tract infections. Of 91 patients with significant bacteriuria, 61 (67%) were cured of their original infection; this was similar to the 54 to 79% cure rates reported in unselected populations of women of a wide age range treated for acute uncomplicated urinary...

Isolation and identification of Vibrio cholerae from poultry and poult ry e n v ironment of Bangladesh were made to check their dis tribution and suscept ib ilit y to selected antimirobials . Isolated s trains were identified following s tandard cultural and biochemical tes ts followed by confirmation with latex agglutination tes t of several polyvalent sera. To examine the antibiotic sens itiv...

A 4-year retrospective study showing that we isolated Bordetella holmesii, but not Bordetella pertussis, from patients with pertussis-like symptoms was performed. From 1995 through 1998, we isolated B. holmesii from 32 nasopharyngeal specimens that had been submitted from patients suspected of having pertussis. Previously, B. holmesii had been associated mainly with septicemia and was not thoug...