Abstract Changes in the apparent moduli of cells have been reported to correlate with cell abnormalities and disease. Indentation is commonly used measure these moduli; however, there evidence suggest that indentation protocol employed affects measured moduli, which can affect our understanding how physiological conditions regulate mechanics. Most studies treat as a homogeneous material or simp...

Cell migration is important for the function of many eukaryotic cells. Recently the nucleus has been shown to play an important role in cell motility. After giving an overview of cell motility mechanisms we review what is currently known about the mechanical properties of the nucleus and the connections between it and the cytoskeleton. We also discuss connections to the extracellular matrix and...

Introduction: The use of cell phones is widespread and there are public concerns regarding its possible deleterious effects on human health especially on the pregnancy outcomes. In this study, structural changes of the placenta after applying the cell phone radiation were examined in the mice model.   Materials and methods: For this work, 40 pregnant Balb/C mice were randomly allocated to ...

Several of the best-studied sex differences in the mammalian brain are ascribed to the hormonal control of cell death. This conclusion is based primarily on correlations between pyknotic cell counts in development and counts of mature neurons in adulthood; the molecular mechanisms of hormone-regulated, sexually dimorphic cell death are unknown. We asked whether Bax, a member of the Bcl-2 family...

The position of the division plane affects cell shape and size, as well as tissue organization. Cells of the fission yeast Schizosaccharomyces pombe have a centrally placed nucleus and divide by fission at the cell center. Microtubules (MTs) are required for the central position of the nucleus. Genetic studies lead to the hypothesis that the position of the nucleus may determine the position of...

background: oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ing1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. the objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

Using an indirect immunoperoxidase technique, the location of gastrin-releasing/bombesin-like immunoreactive fibres and cell bodies in the cat brainstem was studied. A moderate or low density of immunoreactive cell bodies was observed in the nucleus of the brachium of the inferior colliculus, pericentral nucleus of the inferior colliculus, ventral nucleus of the lateral lemniscus and in the ext...