نتایج جستجو برای: cecal ligation and puncture

تعداد نتایج: 16833185  

2016
Hai-Yan Yin Pei Tao Jian-Rui Wei Rui Zhang Yong-Hui Ma

We aim to observe the protective effects of curcumin in hepatocytes in septic rat. Sprague-Dawley rats were randomly divided into six groups of 20 rats each: sham group; model group; xuebijing group; low dose group (50 mg/kg), middle dose group (100 mg/kg) and high dose group (150 mg/kg). Another 60 rats were randomly divided into the six above-mentioned experimental groups of 10 rats each to d...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2015
Nadir Yehya Yi Xin Yousi Oquendo Maurizio Cereda Rahim R Rizi Susan S Margulies

Sepsis is a leading cause of respiratory failure requiring mechanical ventilation, but the interaction between sepsis and ventilation is unclear. While prior studies demonstrated a priming role with endotoxin, actual septic animal models have yielded conflicting results regarding the role of preceding sepsis on development of subsequent ventilator-induced lung injury (VILI). Using a rat cecal l...

Journal: :Signa Vitae 2021

Background: The aim of this work was to investigate whether Follistatin like 1 (FSTL1) exerted an effect on acute kidney injury (AKI) induced by sepsis, and explore the molecular mechanism. Methods: A cecal ligation puncture (CLP) model established adenoviral solution administrated newborn rats achieve FSTL1 knockdown. Colorimetric assays measured concentrations serum creatinine blood urea nitr...

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