نتایج جستجو برای: cd56
تعداد نتایج: 2742 فیلتر نتایج به سال:
IL-2 and IL-15 are lymphocyte growth factors produced by different cell types with overlapping functions in immune responses. Both cytokines costimulate lymphocyte proliferation and activation, while IL-15 additionally promotes the development and survival of NK cells, NKT cells, and intraepithelial lymphocytes. We have investigated the effects of IL-2 and IL-15 on proliferation, cytotoxicity, ...
Our understanding of how mesodermal tissue is formed has been limited by the absence of specific and reliable markers of early mesoderm commitment. We report that mesoderm commitment from human embryonic stem cells (hESCs) is initiated by epithelial-to-mesenchymal transition (EMT) as shown by gene expression profiling and by reciprocal changes in expression of the cell surface proteins, EpCAM/C...
We read with interest the recent paper by KATCHAR et al. [1] reporting the characterisation of natural killer (NK) cells and CD56+ T-cells in sarcoidosis patients. The authors observed that, in the lung of patients with pulmonary sarcoidosis, NK cells have a distinct phenotype. They produce cytokines and participate actively in the T-helper (Th)-1-like inflammatory response. In addition, althou...
Natural killer (NK) cells are innate immune lymphocytes that play critical roles in host defense against viral infection and surveillance against malignant transformation. Long noncoding RNAs (lncRNAs) are important immune system regulators. Here, we analyzed human primary lymphocyte lncRNA expression profiles to identify NK-lncRNA signatures. We detected numerous novel NK-specific lncRNAs with...
سابقه و هدف: هدف از تحقیق حاضر بررسی رابطه بین لنفوسیت های T (CD8+, CD4+)، نسبت CD4+/CD8+ و سلول های کشنده طبیعی (CD56+) با حداکثر نبض اکسیژن در دختران فعال در پاسخ به فعالیت بدنی شدید بود. مواد و روش ها: این مطالعه نیمه تجربی با طرح اندازه های تکراری بر روی 16 دختر فعال 25-20 ساله انجام شد. جهت برآورد حداکثر نبض اکسیژن و پاسخ شاخص های ایمنی از آزمون نوارگردان (GTX) استفاده گردید. نمونه ...
BACKGROUND CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use or heroin use plus HCV infection on the CD56(+) T cell frequency and function. METHODOLOGY/PRINCIPAL FINDINGS A total of 37 heroi...
AIM We aimed to evaluate four immunohistochemical markers (HBME-1, Galectin-3, Cytokeratin-19 and CD56) used alone or in panels in a series of papillary thyroid carcinoma (PTC) and thyroid tumors of uncertain malignant potential (TT-UMP) cases. MATERIALS AND METHODS We performed an immunohistochemical analysis on a tissue micro-array of 11 PTCs [six classic (CPTC), five follicular variant (FV...
CD3(+)CD56(+) NKT-like cells are one of the critical effectors in the immune response to viral infection and tumors, but the functional features of NKT-like cells in HIV infection have been rarely reported. In this study, we observed and described the state of NKT-like cell functions in primary HIV-infected individuals (PHIs), chronic HIV-infected individuals (CHIs), long-term nonprogressors (L...
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