نتایج جستجو برای: cataracts
تعداد نتایج: 3603 فیلتر نتایج به سال:
Aim: The purpose of this study was to evaluate the efficacy and safety complications following combined pars plana vitrectomy phacoemulsification surgery eyes for management vitreous hemorrhage due proliferative diabetic retinopathy as well pronounced cataracts.
 Material Method: Phacoemulsification 23G procedures were performed cataracts. Age, gender, best-corrected visual acuity before a...
Age-related cataracts are one of the leading causes of visual impairment and blindness among the elderly worldwide. Among age-related cataracts, cortical opacities rank as the second most common type; however, little is known about their molecular pathogenesis or genetics. To identify susceptibility loci for cortical cataracts, we genotyped a subset of families (102 families; n = 224 sib pairs)...
PURPOSE To investigate the general clinical features of congenital cataracts and to determine their relationship to visual prognosis and surgical complications according to age at operation and surgical procedure adopted. METHOD We retrospectively evaluated 92 eyes in 61 patients with congenital cataracts who underwent cataract surgery between January 1996 and December 2006. The demographic d...
Cataracts are a significant public health problem with no proven methods for prevention. Discovery of novel disease mechanisms to delineate new therapeutic targets is of importance in cataract prevention and therapy. Herein, we report that mutations in the RagA GTPase (RRAGA), a key regulator of the mechanistic rapamycin complex 1 (mTORC1), are associated with autosomal dominant cataracts. We p...
Limited research is available on how well visual cues integrate with auditory cues to improve speech intelligibility in persons with visual impairments, such as cataracts. We investigated whether simulated cataracts interfered with participants' ability to use visual cues to help disambiguate a spoken message in the presence of spoken background noise. We tested 21 young adults with normal visu...
BACKGROUND Juvenile-onset cataracts are known among the Hutterites of North America. Despite being identified over 30 years ago, this autosomal recessive condition has not been mapped, and the disease gene is unknown. METHODS We performed whole exome sequencing of three Hutterite-type cataract trios and follow-up genotyping and mapping in four extended kindreds. RESULTS Trio exomes enabled ...
PURPOSE The aim of this study was to determine differences in the expression profiles of transforming growth factor (TGF) β isoforms in the fragments of anterior lens capsules (ALCs) and peripheral blood mononuclear cells (PBMCs) of pediatric patients with congenital and traumatic cataracts. METHODS Forty children with congenital cataracts (19 girls and 21 boys) and 22 children with traumatic...
PURPOSE To investigate the relationship between plasma TDRD7 mRNA and lens transparency, and to evaluate plasma TDRD7 mRNA as a potential marker for cataracts and its sub-type by quantitatively analyzing human peripheral blood. METHODS Plasma RNA was extracted from 40 patients with cataracts, and 30 normal controls of matched age and gender. Blood cholesterol and fasting glucose were measured...
dear editor: the nuclear denotation due to the leakage from nuclear electricity plant in japan after the giant tsunami is a great concern. there are many possible health effects including induction of ophthalmic disorder on the affected population to the nuclear denotation. indeed the observation on the effect of radioactive leaking from the nuclear plant after the well-known nuclear leakage ...
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