.......................................................................................................................................... 2 Acknowledgments........................................................................................................................... 3 Table of

We have used a strategy for colocalization of Psi (Psi)-tethered ribozymes and targets to demonstrate that Psi sequences are capable of specific interaction in the cytoplasm of both packaging and nonpackaging cells. These results indicate that current in vitro dimerization models may have in vivo counterparts. The methodology used may be applied to further genetic analyses on Psi domain interac...

How much space (memory) does one need to solve a system of linear equations, reachability on a directed graph or satisfiability of a Boolean formula? We do not know a good answer to this question but our best algorithms for all of these problems require working memory of size at least linear – that is proportional to the number of variables of the system or the number of vertices in the graphs....

Until recently, protein enzymeswere thought to be the only biologically active catalysts. It was believed that DNA stored the genetic information and that RNA played the role of an intermediate courier between the genetic messages contained in the DNA and the ribosomes, where proteins are synthesized. Other RNAs, like transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), were considered as helper m...