The role of leptin in humans is not yet precisely established. Nevertheless there is increasing evidence revealing that this molecule is involved in the pathogenesis of atherosclerosis as an independent risk factor. From another point of view, however, leptin is already related to known traditional risk factors for accelerated atherogenesis, like obesity. We herein provide the experimental and ...

UNLABELLED Infantile and juvenile obesity is a medical, social and cultural problem, which reaches epidemic proportions worldwide. In Romania, according to the World Health Organization, one out of four Romanians is obese. As far as infantile obesity is concerned, Romania ranks third in Europe. Infantile obesity has a major impact on all body systems and is associated with risk factors for card...

background: recent studies show cardiovascular disease (cvd) risk factors have the tendency to intermingle. integration between some biological and homodynamic risk factors have made the new hypothesis for etiology of cvds. the aim of this study was to determine the clustering pattern of metabolic variables and left ventricular (lv) mass among smoker and non-smoker individuals and the interrela...

background: with regard to increasing cardiovascular disease, developing new and effective strategies to reduce cardiovascular disease risk factors seems to be necessary and self efficacy is an effective factor in selecting appropriate methods to achieve the intended purpose. the purpose of this study was to determine the effect of education on promoting self efficacy in patients with cardiovas...

BACKGROUND Complementary strategies to shift risk factor population distributions and target high-risk individuals are required to reduce the burden of type 2 diabetes and cardiovascular disease (CVD). PURPOSE To examine secular changes in glucose and CVD risk factors over 20 years during an individual and population-based CVD prevention program in Västerbotten County, Sweden. METHODS Popul...

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Lipoprotein (a) [Lp(a)], is present only in humans, Old World nonhuman primates, and the European hedgehog. Lp(a) has many properties in common with low-density lipoprotein (LDL) but contains a unique protein, apo(a), which is structurally different from other apolipoproteins. The size of the apo(a) gene is highly variable, resulting in the protein molecular weight ranging from 300 to 800 kDa; ...

introduction: job stress is one of the main characteristics of modern life which is increasing and has been recognized as an important risk factor of cardiovascular diseases. the present study was conducted to determine the association between job stress at work environment and cardiovascular diseases. materials and methods: a number of 300 persons including 150 cases and 150 controls were cons...

Patients with diabetes show an increased vascular morbidity and mortality that reduces their life expectancy by ~5–15 years (depending on the age at diagnosis) (1). There is convincing evidence from epidemiological and pathophysiological studies that hyperglycemia per se is largely responsible for the harmful effects of the disease. As recently shown by clinical trials, treatment of this condit...

The association of a novel factor with clinical vascular disease must meet the same high standard met by ‘traditional’ risk factors. Serum gamma-glutamyltransferase (GGT) activity is a low-cost, highly sensitive laboratory test: though it is currently considered as an index of hepatobiliary dysfunction and alcohol abuse, pathology studies from our group since 1998 have indicated its possible ro...